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Apoptosis in cancer: from pathogenesis to treatment

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, September 2011
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#30 of 2,437)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
2 news outlets
blogs
3 blogs
twitter
19 X users
patent
2 patents
facebook
5 Facebook pages
wikipedia
1 Wikipedia page

Citations

dimensions_citation
2019 Dimensions

Readers on

mendeley
2798 Mendeley
citeulike
1 CiteULike
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Title
Apoptosis in cancer: from pathogenesis to treatment
Published in
Journal of Experimental & Clinical Cancer Research, September 2011
DOI 10.1186/1756-9966-30-87
Pubmed ID
Authors

Rebecca SY Wong

Abstract

Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions. It is also one of the most studied topics among cell biologists. An understanding of the underlying mechanism of apoptosis is important as it plays a pivotal role in the pathogenesis of many diseases. In some, the problem is due to too much apoptosis, such as in the case of degenerative diseases while in others, too little apoptosis is the culprit. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. The mechanism of apoptosis is complex and involves many pathways. Defects can occur at any point along these pathways, leading to malignant transformation of the affected cells, tumour metastasis and resistance to anticancer drugs. Despite being the cause of problem, apoptosis plays an important role in the treatment of cancer as it is a popular target of many treatment strategies. The abundance of literature suggests that targeting apoptosis in cancer is feasible. However, many troubling questions arise with the use of new drugs or treatment strategies that are designed to enhance apoptosis and critical tests must be passed before they can be used safely in human subjects.

X Demographics

X Demographics

The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2,798 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 4 <1%
United States 3 <1%
Canada 3 <1%
India 3 <1%
Germany 2 <1%
Brazil 2 <1%
South Africa 2 <1%
United Kingdom 2 <1%
Pakistan 2 <1%
Other 16 <1%
Unknown 2759 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 439 16%
Student > Master 416 15%
Student > Ph. D. Student 398 14%
Researcher 173 6%
Student > Doctoral Student 139 5%
Other 344 12%
Unknown 889 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 571 20%
Agricultural and Biological Sciences 396 14%
Medicine and Dentistry 291 10%
Pharmacology, Toxicology and Pharmaceutical Science 168 6%
Chemistry 145 5%
Other 252 9%
Unknown 975 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 49. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2023.
All research outputs
#871,057
of 25,791,495 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#30
of 2,437 outputs
Outputs of similar age
#3,419
of 143,478 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#1
of 16 outputs
Altmetric has tracked 25,791,495 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,437 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 143,478 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.