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High-resolution melting analysis reveals low Plasmodium parasitaemia infections among microscopically negative febrile patients in western Kenya

Overview of attention for article published in Malaria Journal, November 2014
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2 X users

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Title
High-resolution melting analysis reveals low Plasmodium parasitaemia infections among microscopically negative febrile patients in western Kenya
Published in
Malaria Journal, November 2014
DOI 10.1186/1475-2875-13-429
Pubmed ID
Authors

Purity N Kipanga, David Omondi, Paul O Mireji, Patrick Sawa, Daniel K Masiga, Jandouwe Villinger

Abstract

Microscopy and rapid diagnostic tests (RDTs) are common tools for diagnosing malaria, but are deficient in detecting low Plasmodium parasitaemia. A novel molecular diagnostic tool (nPCR-HRM) that combines the sensitivity and specificity of nested PCR (nPCR) and direct PCR-high resolution melting analysis (dPCR-HRM) was developed. To evaluate patterns of anti-malarial drug administration when no parasites are detected, nPCR-HRM was employed to screen blood samples for low parasitaemia from febrile patients without microscopically detectable Plasmodium infections in a rural malaria-endemic setting.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Kenya 2 2%
Unknown 111 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 21 18%
Researcher 20 17%
Student > Ph. D. Student 17 15%
Student > Bachelor 11 10%
Student > Postgraduate 8 7%
Other 21 18%
Unknown 17 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 26 23%
Agricultural and Biological Sciences 21 18%
Medicine and Dentistry 19 17%
Immunology and Microbiology 6 5%
Nursing and Health Professions 3 3%
Other 17 15%
Unknown 23 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2014.
All research outputs
#17,731,702
of 22,770,070 outputs
Outputs from Malaria Journal
#4,842
of 5,555 outputs
Outputs of similar age
#173,054
of 256,836 outputs
Outputs of similar age from Malaria Journal
#69
of 103 outputs
Altmetric has tracked 22,770,070 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,555 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 256,836 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.