Title |
Comparative genomics of first available bovine Anaplasma phagocytophilum genome obtained with targeted sequence capture
|
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Published in |
BMC Genomics, November 2014
|
DOI | 10.1186/1471-2164-15-973 |
Pubmed ID | |
Authors |
Thibaud Dugat, Valentin Loux, Sylvain Marthey, Marco Moroldo, Anne-Claire Lagrée, Henri-Jean Boulouis, Nadia Haddad, Renaud Maillard |
Abstract |
Anaplasma phagocytophilum is a zoonotic and obligate intracellular bacterium transmitted by ticks. In domestic ruminants, it is the causative agent of tick-borne fever, which causes significant economic losses in Europe. As A. phagocytophilum is difficult to isolate and cultivate, only nine genome sequences have been published to date, none of which originate from a bovine strain.Our goals were to; 1/ develop a sequencing methodology which efficiently circumvents the difficulties associated with A. phagocytophilum isolation and culture; 2/ describe the first genome of a bovine strain; and 3/ compare it with available genomes, in order to both explore key genomic features at the species level, and to identify candidate genes that could be specific to bovine strains. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
Unknown | 53 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 13 | 24% |
Student > Ph. D. Student | 10 | 19% |
Student > Master | 9 | 17% |
Student > Doctoral Student | 3 | 6% |
Student > Bachelor | 2 | 4% |
Other | 8 | 15% |
Unknown | 9 | 17% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 21 | 39% |
Veterinary Science and Veterinary Medicine | 12 | 22% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Mathematics | 1 | 2% |
Business, Management and Accounting | 1 | 2% |
Other | 4 | 7% |
Unknown | 11 | 20% |