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Genomics and infectious disease: a call to identify the ethical, legal and social implications for public health and clinical practice

Overview of attention for article published in Genome Medicine, November 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

blogs
1 blog
twitter
10 X users
facebook
2 Facebook pages

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
129 Mendeley
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Title
Genomics and infectious disease: a call to identify the ethical, legal and social implications for public health and clinical practice
Published in
Genome Medicine, November 2014
DOI 10.1186/s13073-014-0106-2
Pubmed ID
Authors

Gail Geller, Rachel Dvoskin, Chloe L Thio, Priya Duggal, Michelle H Lewis, Theodore C Bailey, Andrea Sutherland, Daniel A Salmon, Jeffrey P Kahn

Abstract

Advances in genomics are contributing to the development of more effective, personalized approaches to the prevention and treatment of infectious diseases. Genetic sequencing technologies are furthering our understanding of how human and pathogen genomic factors - and their interactions - contribute to individual differences in immunologic responses to vaccines, infections and drug therapies. Such understanding will influence future policies and procedures for infectious disease management. With the potential for tailored interventions for particular individuals, populations or subpopulations, ethical, legal and social implications (ELSIs) may arise for public health and clinical practice. Potential considerations include balancing health-related benefits and harms between individuals and the larger community, minimizing threats to individual privacy and autonomy, and ensuring just distribution of scarce resources. In this Opinion, we consider the potential application of pathogen and host genomic information to particular viral infections that have large-scale public health consequences but differ in ELSI-relevant characteristics such as ease of transmission, chronicity, severity, preventability and treatability. We argue for the importance of anticipating these ELSI issues in advance of new scientific discoveries, and call for the development of strategies for identifying and exploring ethical questions that should be considered as clinical, public health and policy decisions are made.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 128 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 17%
Student > Master 21 16%
Student > Bachelor 19 15%
Student > Ph. D. Student 10 8%
Other 9 7%
Other 22 17%
Unknown 26 20%
Readers by discipline Count As %
Medicine and Dentistry 24 19%
Biochemistry, Genetics and Molecular Biology 22 17%
Agricultural and Biological Sciences 20 16%
Nursing and Health Professions 5 4%
Social Sciences 5 4%
Other 22 17%
Unknown 31 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2015.
All research outputs
#2,108,555
of 25,711,998 outputs
Outputs from Genome Medicine
#462
of 1,608 outputs
Outputs of similar age
#27,867
of 371,830 outputs
Outputs of similar age from Genome Medicine
#14
of 45 outputs
Altmetric has tracked 25,711,998 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,608 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 371,830 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.