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Mendeley readers
Attention Score in Context
| Title |
Evaluation of permanent alopecia in pediatric medulloblastoma patients treated with proton radiation
|
|---|---|
| Published in |
Radiation Oncology, November 2014
|
| DOI | 10.1186/s13014-014-0220-8 |
| Pubmed ID | |
| Authors |
Chul Hee Min, Harald Paganetti, Brian A Winey, Judith Adams, Shannon M MacDonald, Nancy J Tarbell, Torunn I Yock |
| Abstract |
BackgroundTo precisely calculate skin dose and thus to evaluate the relationship between the skin dose and permanent alopecia for pediatric medulloblastoma patients treated with proton beams.MethodsThe dosimetry and alopecia outcomes of 12 children with medulloblastoma (ages 4-15 years) comprise the study cohort. Permanent alopecia was assessed and graded after completion of the entire therapy. Skin threshold doses of permanent alopecia were calculated based on the skin dose from the craniospinal irradiation (CSI) plan using the concept of generalized equivalent uniform dose (gEUD) and accounting for chemotherapy intensity. Monte Carlo simulations were employed to accurately assess uncertainties due to beam range prediction and secondary particles.ResultsIncreasing the dose of the CSI field or the dose given by the boost field to the posterior fossa increased total skin dose delivered in that region. It was found that permanent alopecia could be correlated with CSI dose with a threshold of about 21 Gy (relative biological effectiveness, RBE) with high dose chemotherapy and 30 Gy(RBE) with conventional chemotherapy.ConclusionsOur results based on 12 patients provide a relationship between the skin dose and permanent alopecia for pediatric medulloblastoma patients treated with protons. The alopecia risk as assessed with gEUD could be predicted based on the treatment plan information. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 33% |
| United States | 1 | 33% |
| United Kingdom | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Unknown | 34 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 14% |
| Student > Master | 4 | 11% |
| Researcher | 3 | 9% |
| Student > Ph. D. Student | 3 | 9% |
| Professor | 2 | 6% |
| Other | 9 | 26% |
| Unknown | 9 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 34% |
| Physics and Astronomy | 6 | 17% |
| Nursing and Health Professions | 5 | 14% |
| Business, Management and Accounting | 1 | 3% |
| Psychology | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 10 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2017.
All research outputs
#7,014,281
of 25,626,416 outputs
Outputs from Radiation Oncology
#286
of 2,111 outputs
Outputs of similar age
#88,460
of 371,291 outputs
Outputs of similar age from Radiation Oncology
#7
of 73 outputs
Altmetric has tracked 25,626,416 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 2,111 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 371,291 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.