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β Cell Replacement Therapy

Overview of attention for article published in Transplantation, February 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

twitter
13 tweeters

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
37 Mendeley
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Title
β Cell Replacement Therapy
Published in
Transplantation, February 2018
DOI 10.1097/tp.0000000000001937
Pubmed ID
Authors

Christian Schuetz, Takayuki Anazawa, Sarah E. Cross, Leticia Labriola, Raphael P.H. Meier, Robert R. Redfield, Hanne Scholz, Peter G. Stock, Nathan W. Zammit

Abstract

ß cell replacement with either pancreas or islet transplantation has progressed immensely over the last decades with current 1- and 5-year insulin independence rates of ~85% and ~50%, respectively. Recent advances are largely attributed to improvements in immunosuppressive regimen, donor selection and surgical technique. However, both strategies are compromised by a scarce donor source. Xenotransplantation provides a potential solution by providing a theoretically unlimited supply of islets, but clinical application has been limited by concerns for a potent immune response against xenogeneic tissue. ß cell clusters derived from embryonic or induced pluripotent stem (iPS) cells represent another promising unlimited source of insulin producing cells, but clinical application is pending further advances in the function of the ß cell like clusters. Exciting developments and rapid progress in all areas of ß cell replacement prompted a lively debate by members of the young investigator committee of the International Pancreas and Islet Transplant Association (IPITA) at the 15th IPITA Congress in Melbourne and at the 26th international congress of The Transplant Society (TTS) in Hong Kong. This international group of young investigators debated which modality of ß cell replacement would predominate the landscape in 10 years, and their arguments are summarized here.

Twitter Demographics

The data shown below were collected from the profiles of 13 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 19%
Researcher 5 14%
Professor > Associate Professor 3 8%
Unspecified 3 8%
Student > Postgraduate 3 8%
Other 5 14%
Unknown 11 30%
Readers by discipline Count As %
Medicine and Dentistry 11 30%
Biochemistry, Genetics and Molecular Biology 4 11%
Unspecified 3 8%
Agricultural and Biological Sciences 3 8%
Engineering 3 8%
Other 1 3%
Unknown 12 32%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2020.
All research outputs
#2,254,082
of 15,094,246 outputs
Outputs from Transplantation
#443
of 6,018 outputs
Outputs of similar age
#77,592
of 406,782 outputs
Outputs of similar age from Transplantation
#20
of 76 outputs
Altmetric has tracked 15,094,246 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,018 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 406,782 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.