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Double trouble: a patient with both HLA-B27 anterior uveitis and HLA-A29 birdshot chorioretinitis

Overview of attention for article published in Journal of Ophthalmic Inflammation and Infection, November 2014
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Mentioned by

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1 tweeter
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1 Facebook page

Readers on

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10 Mendeley
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Title
Double trouble: a patient with both HLA-B27 anterior uveitis and HLA-A29 birdshot chorioretinitis
Published in
Journal of Ophthalmic Inflammation and Infection, November 2014
DOI 10.1186/s12348-014-0028-6
Pubmed ID
Authors

Zeina Haddad, Ashvini Reddy

Abstract

Birdshot chorioretinitis (BSCR) is a rare ocular inflammatory disorder associated with HLA-A29 and characterized by bilateral choroidal lesions, vitritis, macular edema, and retinal vasculitis. Ocular inflammation associated with HLA-B27 is typically a recurrent, unilateral, acute anterior uveitis (AAU) that is frequently associated with ankylosing spondylitis (AS). To date, there are no reports of patients with both HLA-A29-positive BSCR and HLA-B27 AAU/AS in the English literature. A 50-year-old man with a history of bilateral anterior uveitis, vitritis, retinal vasculitis, and cream-colored depigmented oval choroidal lesions was found to be HLA-A29 and HLA-B27 positive. His lumbar spine and sacroiliac joint films revealed fusion of the spine, known as 'bamboo spine' compatible with the diagnosis of ankylosing spondyloarthropathy. He had chronic ocular inflammation that was difficult to control with systemic steroids and immunomodulatory agents. This is the only report of a patient with both HLA-A29-positive BSCR and HLA-B27-positive AS and associated anterior uveitis. The severity of his disease suggests that patients who test positive for both HLA-A29 and HLA-B27 carry a poor visual prognosis. Prompt diagnosis and treatment with local or systemic corticosteroids or steroid-sparing agents may control the disease.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 20%
Other 2 20%
Researcher 2 20%
Unspecified 2 20%
Student > Ph. D. Student 1 10%
Other 1 10%
Readers by discipline Count As %
Medicine and Dentistry 7 70%
Unspecified 2 20%
Energy 1 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2014.
All research outputs
#2,195,667
of 4,571,028 outputs
Outputs from Journal of Ophthalmic Inflammation and Infection
#14
of 72 outputs
Outputs of similar age
#66,727
of 147,059 outputs
Outputs of similar age from Journal of Ophthalmic Inflammation and Infection
#2
of 7 outputs
Altmetric has tracked 4,571,028 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 72 research outputs from this source. They receive a mean Attention Score of 0.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 147,059 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.