Title |
Improved Exercise-Related Skeletal Muscle Oxygen Consumption Following Uptake of Endurance Training Measured Using Near-Infrared Spectroscopy
|
---|---|
Published in |
Frontiers in Physiology, December 2017
|
DOI | 10.3389/fphys.2017.01018 |
Pubmed ID | |
Authors |
Siana Jones, Andrew D'Silva, Anish Bhuva, Guy Lloyd, Charlotte Manisty, James C. Moon, Sanjay Sharma, Alun D. Hughes |
Abstract |
Skeletal muscle metabolic function is known to respond positively to exercise interventions. Developing non-invasive techniques that quantify metabolic adaptations and identifying interventions that impart successful response are ongoing challenges for research. Healthy non-athletic adults (18-35 years old) were enrolled in a study investigating physiological adaptations to a minimum of 16 weeks endurance training prior to undertaking their first marathon. Before beginning training, participants underwent measurements of skeletal muscle oxygen consumption using near-infrared spectroscopy (NIRS) at rest (resting muscle[Formula: see text]O2) and immediately following a maximal exercise test (post-exercise muscle[Formula: see text]O2). Exercise-related increase in muscle[Formula: see text]O2 (Δm[Formula: see text]O2) was derived from these measurements and cardio-pulmonary peak[Formula: see text]O2 measured by analysis of expired gases. All measurements were repeated within 3 weeks of participants completing following the marathon and marathon completion time recorded. Muscle[Formula: see text]O2 was positively correlated with cardio-pulmonary peak[Formula: see text]O2 (r = 0.63, p < 0.001). Muscle[Formula: see text]O2 increased at follow-up (48% increase; p = 0.004) despite no change in cardio-pulmonary peak[Formula: see text]O2 (0% change; p = 0.97). Faster marathon completion time correlated with higher cardio-pulmonary peak[Formula: see text]O2 (rpartial = -0.58, p = 0.002) but not muscle[Formula: see text]O2 (rpartial = 0.16, p = 0.44) after adjustment for age and sex [and adipose tissue thickness (ATT) for muscle[Formula: see text]O2 measurements]. Skeletal muscle metabolic adaptions occur following training and completion of a first-time marathon; these can be identified non-invasively using NIRS. Although the cardio-pulmonary system is limiting for running performance, skeletal muscle changes can be detected despite minimal improvement in cardio-pulmonary function. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 3 | 30% |
Switzerland | 1 | 10% |
Chile | 1 | 10% |
United States | 1 | 10% |
Unknown | 4 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 50% |
Scientists | 4 | 40% |
Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 91 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 15 | 16% |
Student > Ph. D. Student | 10 | 11% |
Student > Master | 10 | 11% |
Researcher | 6 | 7% |
Student > Doctoral Student | 5 | 5% |
Other | 21 | 23% |
Unknown | 24 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Sports and Recreations | 24 | 26% |
Medicine and Dentistry | 13 | 14% |
Biochemistry, Genetics and Molecular Biology | 5 | 5% |
Nursing and Health Professions | 4 | 4% |
Neuroscience | 3 | 3% |
Other | 18 | 20% |
Unknown | 24 | 26% |