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Pluripotent Stem Cells for Schwann Cell Engineering

Overview of attention for article published in Stem Cell Reviews and Reports, November 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

blogs
1 blog
twitter
1 X user
patent
4 patents

Citations

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33 Dimensions

Readers on

mendeley
75 Mendeley
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Title
Pluripotent Stem Cells for Schwann Cell Engineering
Published in
Stem Cell Reviews and Reports, November 2014
DOI 10.1007/s12015-014-9577-1
Pubmed ID
Authors

Ming-San Ma, Erik Boddeke, Sjef Copray

Abstract

Tissue engineering of Schwann cells (SCs) can serve a number of purposes, such as in vitro SC-related disease modeling, treatment of peripheral nerve diseases or peripheral nerve injury, and, potentially, treatment of CNS diseases. SCs can be generated from autologous stem cells in vitro by recapitulating the various stages of in vivo neural crest formation and SC differentiation. In this review, we survey the cellular and molecular mechanisms underlying these in vivo processes. We then focus on the current in vitro strategies for generating SCs from two sources of pluripotent stem cells, namely embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Different methods for SC engineering from ESCs and iPSCs are reviewed and suggestions are proposed for optimizing the existing protocols. Potential safety issues regarding the clinical application of iPSC-derived SCs are discussed as well. Lastly, we will address future aspects of SC engineering.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 1%
Chile 1 1%
United Kingdom 1 1%
Spain 1 1%
United States 1 1%
Unknown 70 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 24%
Researcher 17 23%
Student > Bachelor 12 16%
Student > Master 9 12%
Student > Doctoral Student 3 4%
Other 7 9%
Unknown 9 12%
Readers by discipline Count As %
Medicine and Dentistry 14 19%
Agricultural and Biological Sciences 14 19%
Neuroscience 13 17%
Biochemistry, Genetics and Molecular Biology 10 13%
Engineering 5 7%
Other 8 11%
Unknown 11 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2020.
All research outputs
#2,575,478
of 25,374,917 outputs
Outputs from Stem Cell Reviews and Reports
#54
of 1,036 outputs
Outputs of similar age
#34,575
of 369,510 outputs
Outputs of similar age from Stem Cell Reviews and Reports
#2
of 13 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,036 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,510 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.