Title |
Unique aspects of fiber degradation by the ruminal ethanologen Ruminococcus albus 7 revealed by physiological and transcriptomic analysis
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Published in |
BMC Genomics, December 2014
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DOI | 10.1186/1471-2164-15-1066 |
Pubmed ID | |
Authors |
Melissa R Christopherson, John A Dawson, David M Stevenson, Andrew C Cunningham, Shanti Bramhacharya, Paul J Weimer, Christina Kendziorski, Garret Suen |
Abstract |
Bacteria in the genus Ruminococcus are ubiquitous members of the mammalian gastrointestinal tract. In particular, they are important in ruminants where they digest a wide range of plant cell wall polysaccharides. For example, Ruminococcus albus 7 is a primary cellulose degrader that produces acetate usable by its bovine host. Moreover, it is one of the few organisms that ferments cellulose to form ethanol at mesophilic temperatures in vitro. The mechanism of cellulose degradation by R. albus 7 is not well-defined and is thought to involve pilin-like proteins, unique carbohydrate-binding domains, a glycocalyx, and cellulosomes. Here, we used a combination of comparative genomics, fermentation analyses, and transcriptomics to further clarify the cellulolytic and fermentative potential of R. albus 7. |
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United States | 1 | 100% |
Demographic breakdown
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 23 | 28% |
Student > Master | 12 | 14% |
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Student > Bachelor | 8 | 10% |
Professor | 4 | 5% |
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Nursing and Health Professions | 1 | 1% |
Other | 8 | 10% |
Unknown | 21 | 25% |