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68Ga-DOTA-Siglec-9 PET/CT imaging of peri-implant tissue responses and staphylococcal infections

Overview of attention for article published in EJNMMI Research, August 2014
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Title
68Ga-DOTA-Siglec-9 PET/CT imaging of peri-implant tissue responses and staphylococcal infections
Published in
EJNMMI Research, August 2014
DOI 10.1186/s13550-014-0045-3
Pubmed ID
Authors

Helena Ahtinen, Julia Kulkova, Laura Lindholm, Erkki Eerola, Antti J Hakanen, Niko Moritz, Mirva Söderström, Tiina Saanijoki, Sirpa Jalkanen, Anne Roivainen, Hannu T Aro

Abstract

Staphylococcus epidermidis (S. epidermidis) has emerged as one of the leading pathogens of biomaterial-related infections. Vascular adhesion protein-1 (VAP-1) is an inflammation-inducible endothelial molecule controlling extravasation of leukocytes. Sialic acid-binding immunoglobulin-like lectin 9 (Siglec-9) is a leukocyte ligand of VAP-1. We hypothesized that (68)Ga-labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated Siglec-9 motif containing peptide ((68)Ga-DOTA-Siglec-9) could detect inflammatory response due to S. epidermidis peri-implant infection by positron emission tomography (PET).

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 2 4%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 24%
Student > Master 6 13%
Student > Ph. D. Student 6 13%
Student > Bachelor 3 7%
Student > Doctoral Student 2 4%
Other 10 22%
Unknown 7 16%
Readers by discipline Count As %
Medicine and Dentistry 11 24%
Agricultural and Biological Sciences 5 11%
Pharmacology, Toxicology and Pharmaceutical Science 4 9%
Chemistry 4 9%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 9 20%
Unknown 10 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2014.
All research outputs
#20,246,428
of 22,774,233 outputs
Outputs from EJNMMI Research
#384
of 555 outputs
Outputs of similar age
#193,903
of 230,515 outputs
Outputs of similar age from EJNMMI Research
#3
of 4 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 555 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.