Title |
Mechanical colon cleansing for screening colonoscopy: A randomized controlled trial
|
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Published in |
Journal of Digestive Diseases, January 2018
|
DOI | 10.1111/1751-2980.12562 |
Pubmed ID | |
Authors |
Kamran Ayub, Gyanprakash Ketwaroo, Suhaib Abudayyeh, Abeer Ibrahim, Rhonda A Cole, Rosetta Brumfield‐Brown, Waqar A Qureshi, Linda Rabeneck, David Y Graham |
Abstract |
Effective screening colonoscopy depends on the quality of colon preparation. To compare pulsed irrigation evacuation (PIE), polyethylene glycol (PEG) and sodium phosphate colon preps. Outpatients at a VA hospital were randomized using sealed envelopes. Preparations consisted of: 4 liters Golytely; 90 mL of Fleet sodium phosphate with 4-6 glasses water b.i.d., and 296 mL of Mg citrate in the evening with PIE prior to colonoscopy. Colon cleansing was assessed blindly using a 5-point scale: 0 = very poor to 4 = excellent. 391 patients participated (PEG = 129, sodium phosphate = 127, PIE = 135); mean age: 62 years, 75% men. PIE and sodium phosphate were superior to PEG: median cleansing = 4 (excellent) vs. 3 with PEG (p <0.01). Inadequate preps were more common with PEG than PIE (18% vs. 5%) (p <0.01). Side effects including: vomiting: 37% with the sodium phosphate vs. 5% with PEG and 2% with PIE (p<0.01). The 3 preps were judged as intolerable in <5%. PIE and sodium phosphate were superior to PEG for colon preparations. PIE would be the preferred preparation for those at high risk for unsatisfactory preparations or with unsatisfactory traditional preparations. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 22% |
Student > Master | 3 | 17% |
Student > Ph. D. Student | 2 | 11% |
Other | 1 | 6% |
Researcher | 1 | 6% |
Other | 1 | 6% |
Unknown | 6 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 4 | 22% |
Nursing and Health Professions | 3 | 17% |
Arts and Humanities | 1 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Sports and Recreations | 1 | 6% |
Other | 1 | 6% |
Unknown | 7 | 39% |