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The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression

Overview of attention for article published in Archivum Immunologiae et Therapiae Experimentalis, December 2017
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Title
The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression
Published in
Archivum Immunologiae et Therapiae Experimentalis, December 2017
DOI 10.1007/s00005-017-0494-2
Pubmed ID
Authors

Chon-Kit Chou, Ya-Ting Yang, Ho-Chun Yang, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Hui-Min David Wang, Eing-Mei Tsai, Chien-Chih Chiu

Abstract

Di(2-ethylhexyl)phthalate (DEHP), a widely used plasticizer, mainly serves as an additive to render polyvinyl chloride (PVC) soft and flexible. PVC plastics have become ubiquitous in our modern society. Yet, the leaching of DEHP from PVC-based consumables ultimately results in the deposition in certain tissues via inadvertent applications. Health risks for human populations exposed to DEHP has been assumed by studies on rodents and other species, including the DEHP-induced developmental dysregulation, reproductive impairments, tumorigenesis, and diseases in a transgenerational manner. In this review, we comprehensively summarize the accumulated literature regarding the multifaceted roles of DEHP in the activation of the nuclear receptors, the alteration of the redox homeostasis, epigenetic modifications and the acquisition of chemoresistance.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 14%
Student > Ph. D. Student 3 14%
Other 2 9%
Student > Bachelor 2 9%
Student > Master 2 9%
Other 2 9%
Unknown 8 36%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 32%
Agricultural and Biological Sciences 3 14%
Environmental Science 2 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Nursing and Health Professions 1 5%
Other 1 5%
Unknown 7 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2018.
All research outputs
#18,578,649
of 23,011,300 outputs
Outputs from Archivum Immunologiae et Therapiae Experimentalis
#280
of 384 outputs
Outputs of similar age
#327,145
of 439,586 outputs
Outputs of similar age from Archivum Immunologiae et Therapiae Experimentalis
#6
of 8 outputs
Altmetric has tracked 23,011,300 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 384 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,586 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.