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Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytes

Overview of attention for article published in Arthritis Research & Therapy, January 2012
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Mentioned by

peer_reviews
1 peer review site

Citations

dimensions_citation
8 Dimensions

Readers on

mendeley
14 Mendeley
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Title
Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytes
Published in
Arthritis Research & Therapy, January 2012
DOI 10.1186/ar4045
Pubmed ID
Authors

Giorgio Gasparini, Marco Gori, Francesco Paonessa, Eusebio Chiefari, Antonio Brunetti, Olimpio Galasso

Abstract

Insulin-like growth factor I (IGF-I) regulates articular cartilage homeostasis. During osteoarthritis (OA), the anabolic responses of chondrocytes to IGF-I are likely to be prevented by the enhanced production of IGF-binding proteins (IGFBPs), especially IGFBP-3. The aim of this study is to evaluate whether the architectural transcription factor high mobility group A1 (HMGA1) influences IGFBP-3 overexpression in vitro, in cultured chondrocytic cell lines, and ex vivo, in human osteoarthritic cartilage compared to healthy human cartilage controls.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 7%
Unknown 13 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 21%
Researcher 2 14%
Student > Master 2 14%
Professor 2 14%
Unspecified 1 7%
Other 3 21%
Unknown 1 7%
Readers by discipline Count As %
Medicine and Dentistry 4 29%
Agricultural and Biological Sciences 4 29%
Biochemistry, Genetics and Molecular Biology 2 14%
Psychology 1 7%
Unspecified 1 7%
Other 0 0%
Unknown 2 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 December 2014.
All research outputs
#2,412,013
of 4,691,823 outputs
Outputs from Arthritis Research & Therapy
#646
of 1,141 outputs
Outputs of similar age
#78,935
of 155,522 outputs
Outputs of similar age from Arthritis Research & Therapy
#28
of 52 outputs
Altmetric has tracked 4,691,823 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,141 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 155,522 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.