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Immunity, safety and protection of an Adenovirus 5 prime - Modified Vaccinia virus Ankara boost subunit vaccine against Mycobacterium avium subspecies paratuberculosis infection in calves

Overview of attention for article published in Veterinary Research, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
1 news outlet
patent
1 patent
facebook
3 Facebook pages

Citations

dimensions_citation
16 Dimensions

Readers on

mendeley
80 Mendeley
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Title
Immunity, safety and protection of an Adenovirus 5 prime - Modified Vaccinia virus Ankara boost subunit vaccine against Mycobacterium avium subspecies paratuberculosis infection in calves
Published in
Veterinary Research, October 2014
DOI 10.1186/s13567-014-0112-9
Pubmed ID
Authors

Tim J Bull, Christina Vrettou, Richard Linedale, Catherine McGuinnes, Sam Strain, Jim McNair, Sarah C Gilbert, Jayne C Hope

Abstract

Ketamine is widely used in equine anaesthesia. Beside its anaesthetic and analgesic properties, ketamine possesses a cytokine-modulating activity. However, to date, no data are available regarding the inhibitory effect of ketamine on the cytokine response in horses. In horses, cytokines such as tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) play a pivotal role in the pathogenesis of equine endotoxaemia following gastrointestinal disorders. Hence, the objective of this study was to assess the influence of ketamine on LPS-induced TNF-alpha and IL-6 formation in an equine macrophage cell line (eCAS cells). The results demonstrate a cytokine-modulating activity of ketamine in an equine cell line, suggesting a beneficial role for ketamine in the treatment of equine endotoxaemia.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Poland 1 1%
South Africa 1 1%
Unknown 77 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 16%
Student > Bachelor 11 14%
Student > Ph. D. Student 7 9%
Student > Postgraduate 3 4%
Professor 3 4%
Other 13 16%
Unknown 30 38%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 19%
Veterinary Science and Veterinary Medicine 9 11%
Pharmacology, Toxicology and Pharmaceutical Science 6 8%
Immunology and Microbiology 6 8%
Biochemistry, Genetics and Molecular Biology 4 5%
Other 6 8%
Unknown 34 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2021.
All research outputs
#2,768,542
of 22,776,824 outputs
Outputs from Veterinary Research
#110
of 1,200 outputs
Outputs of similar age
#33,822
of 260,660 outputs
Outputs of similar age from Veterinary Research
#3
of 25 outputs
Altmetric has tracked 22,776,824 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,200 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,660 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.