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Heart–kidney crosstalk and role of humoral signaling in critical illness

Overview of attention for article published in Critical Care, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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22 X users
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1 Facebook page

Citations

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90 Dimensions

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90 Mendeley
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Title
Heart–kidney crosstalk and role of humoral signaling in critical illness
Published in
Critical Care, January 2014
DOI 10.1186/cc13177
Pubmed ID
Authors

Grazia Maria Virzì, Sonya Day, Massimo de Cal, Giorgio Vescovo, Claudio Ronco

Abstract

Organ failure in the heart or kidney can initiate various complex metabolic, cell-mediated and humoral pathways affecting distant organs, contributing to the high therapeutic costs and significantly higher morbidity and mortality. The universal outreach of cells in an injured state has myriad consequences to distant organ cells and their milieu. Heart performance and kidney function are closely interconnected and communication between these organs occurs through a variety of bidirectional pathways. The term cardiorenal syndrome (CRS) is often used to describe this condition and represents an important model for exploring the pathophysiology of cardiac and renal dysfunction. Clinical evidence suggests that tissue injury in both acute kidney injury and heart failure has immune-mediated inflammatory consequences that can initiate remote organ dysfunction. Acute cardiorenal syndrome (CRS type 1) and acute renocardiac syndrome (CRS type 3) are particularly relevant in high-acuity medical units. This review briefly summarizes relevant research and focuses on the role of signaling in heart-kidney crosstalk in the critical care setting.

X Demographics

X Demographics

The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 1%
Italy 1 1%
Brazil 1 1%
Unknown 87 97%

Demographic breakdown

Readers by professional status Count As %
Other 12 13%
Student > Ph. D. Student 11 12%
Student > Master 10 11%
Student > Postgraduate 8 9%
Professor > Associate Professor 8 9%
Other 23 26%
Unknown 18 20%
Readers by discipline Count As %
Medicine and Dentistry 55 61%
Biochemistry, Genetics and Molecular Biology 10 11%
Immunology and Microbiology 2 2%
Nursing and Health Professions 1 1%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Other 1 1%
Unknown 20 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2015.
All research outputs
#2,643,419
of 25,371,288 outputs
Outputs from Critical Care
#2,300
of 6,554 outputs
Outputs of similar age
#29,438
of 318,884 outputs
Outputs of similar age from Critical Care
#14
of 90 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,884 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.