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ALS patients with cognitive impairment (ALSci) have a worse prognosis, but we dont know why. We previously showed ALSci patients have synapse loss in their frontal cortex (https://t.co/igEfZ9soDh), so we wanted to check their synaptic proteome for clues.
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Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis. https://t.co/hdX9ZMQLEE
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RT @TSpiresJones: In case you didn't read it in 2017, check out our new paper on synapse loss in #ALS, a great way to start the new year ht…