Title |
Acupuncture for chronic prostatitis/chronic pelvic pain syndrome: study protocol for a randomized controlled trial
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Published in |
Trials, December 2017
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DOI | 10.1186/s13063-017-2383-8 |
Pubmed ID | |
Authors |
Zongshi Qin, Yan Liu, Kehua Zhou, Jiani Wu, Ran Pang, Ning Li, Chang Xu, Joey S. W. Kwong, Zhishun Liu |
Abstract |
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition affecting men of all ages. Acupuncture may be an effective treatment option for CP/CPPS, but evidence is limited. We propose to evaluate the effectiveness of acupuncture in a rigorously conducted trial. Ten hospitals will recruit 440 participants with CP/CPPS in China from October 2017 to December 2019. Participants will be randomly allocated to acupuncture or sham acupuncture with a 1:1 ratio using computerized simple random sampling. The whole study consists of 2-week baseline, 8-week treatment, and 24-week follow up. Twenty 30-mintute sessions of acupuncture or sham acupuncture treatment will be provided between week 1 and 8. The two co-primary outcomes are the proportion of responders at week 8 and week 32. Secondary outcomes include proportion of responders in the two groups at different time points; change in the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) total score; change in the NIH-CPSI subscales; change in the International Prostate Symptom Score; change in the Hospital Anxiety and Depression Scale; expectation assessments; proportions of participants in each response category of the Global Response Assessment; change in the International Index of Erectile Function 5; change in the five-level EuroQol five-dimensional questionnaire and a visual analogue scale; and changes in peak and average urinary flow rate. This study will provide robust evidence on whether acupuncture is effective for relieving symptoms of CP/CPPS. ClinicalTrials.gov, NCT03213938. Registered on 5 July 2017. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Philippines | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 69 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 9 | 13% |
Student > Bachelor | 8 | 12% |
Researcher | 7 | 10% |
Student > Ph. D. Student | 6 | 9% |
Student > Master | 6 | 9% |
Other | 12 | 17% |
Unknown | 21 | 30% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 24 | 35% |
Nursing and Health Professions | 5 | 7% |
Psychology | 4 | 6% |
Neuroscience | 3 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Other | 4 | 6% |
Unknown | 27 | 39% |