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Misoprostol for medical treatment of missed abortion: a systematic review and network meta-analysis

Overview of attention for article published in Scientific Reports, May 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

twitter
4 tweeters
wikipedia
1 Wikipedia page

Citations

dimensions_citation
11 Dimensions

Readers on

mendeley
59 Mendeley
Title
Misoprostol for medical treatment of missed abortion: a systematic review and network meta-analysis
Published in
Scientific Reports, May 2017
DOI 10.1038/s41598-017-01892-0
Pubmed ID
Authors

Hang-lin Wu, Sheeba Marwah, Pei Wang, Qiu-meng Wang, Xiao-wen Chen

Abstract

The efficacy and safety of misoprostol alone for missed abortion varied with different regimens. To evaluate existing evidence for the medical management of missed abortion using misoprostol, we undertook a comprehensive review and meta-analysis. The electronic literature search was conducted using PubMed, the Cochrane Library, Embase, EBSCOhost Online Research Databases, Springer Link, ScienceDirect, Web of Science, Ovid Medline and Google Scholar. 18 studies of 1802 participants were included in our analysis. Compared with vaginal misoprostol of 800 ug or sublingual misoprostol of 600 ug, lower-dose regimens (200 ug or 400 ug) by any route of administration tend to be significantly less effective in producing abortion within about 24 hours. In terms of efficacy, the most effective treatment was sublingual misoprostol of 600 ug and the least effective was oral misoprostol of 400 ug. In terms of tolerability, vaginal misoprostol of 400 ug was reported with fewer side effects and sublingual misoprostol of 600 ug was reported with more side effects. Misoprostol is a non-invasive, effective medical method for completion of abortion in missed abortion. Sublingual misoprostol of 600 ug or vaginal misoprostol of 800 ug may be a good choice for the first dose. The ideal dose and medication interval of misoprostol however needs to be further researched.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 59 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 19%
Student > Postgraduate 9 15%
Student > Bachelor 9 15%
Other 6 10%
Student > Ph. D. Student 6 10%
Other 8 14%
Unknown 10 17%
Readers by discipline Count As %
Medicine and Dentistry 30 51%
Nursing and Health Professions 5 8%
Business, Management and Accounting 3 5%
Economics, Econometrics and Finance 2 3%
Agricultural and Biological Sciences 1 2%
Other 7 12%
Unknown 11 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2019.
All research outputs
#2,808,407
of 15,175,914 outputs
Outputs from Scientific Reports
#21,174
of 78,196 outputs
Outputs of similar age
#96,574
of 403,935 outputs
Outputs of similar age from Scientific Reports
#3,288
of 13,285 outputs
Altmetric has tracked 15,175,914 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 78,196 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 403,935 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 13,285 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.