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Misoprostol for medical treatment of missed abortion: a systematic review and network meta-analysis

Overview of attention for article published in Scientific Reports, May 2017
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

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4 news outlets
twitter
8 X users
wikipedia
3 Wikipedia pages

Citations

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54 Dimensions

Readers on

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182 Mendeley
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Title
Misoprostol for medical treatment of missed abortion: a systematic review and network meta-analysis
Published in
Scientific Reports, May 2017
DOI 10.1038/s41598-017-01892-0
Pubmed ID
Authors

Hang-lin Wu, Sheeba Marwah, Pei Wang, Qiu-meng Wang, Xiao-wen Chen

Abstract

The efficacy and safety of misoprostol alone for missed abortion varied with different regimens. To evaluate existing evidence for the medical management of missed abortion using misoprostol, we undertook a comprehensive review and meta-analysis. The electronic literature search was conducted using PubMed, the Cochrane Library, Embase, EBSCOhost Online Research Databases, Springer Link, ScienceDirect, Web of Science, Ovid Medline and Google Scholar. 18 studies of 1802 participants were included in our analysis. Compared with vaginal misoprostol of 800 ug or sublingual misoprostol of 600 ug, lower-dose regimens (200 ug or 400 ug) by any route of administration tend to be significantly less effective in producing abortion within about 24 hours. In terms of efficacy, the most effective treatment was sublingual misoprostol of 600 ug and the least effective was oral misoprostol of 400 ug. In terms of tolerability, vaginal misoprostol of 400 ug was reported with fewer side effects and sublingual misoprostol of 600 ug was reported with more side effects. Misoprostol is a non-invasive, effective medical method for completion of abortion in missed abortion. Sublingual misoprostol of 600 ug or vaginal misoprostol of 800 ug may be a good choice for the first dose. The ideal dose and medication interval of misoprostol however needs to be further researched.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 182 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 182 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 14%
Student > Master 17 9%
Student > Postgraduate 14 8%
Researcher 12 7%
Other 11 6%
Other 33 18%
Unknown 69 38%
Readers by discipline Count As %
Medicine and Dentistry 69 38%
Nursing and Health Professions 11 6%
Biochemistry, Genetics and Molecular Biology 5 3%
Unspecified 4 2%
Business, Management and Accounting 3 2%
Other 19 10%
Unknown 71 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 44. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2023.
All research outputs
#892,155
of 24,637,659 outputs
Outputs from Scientific Reports
#9,368
of 134,452 outputs
Outputs of similar age
#18,360
of 315,290 outputs
Outputs of similar age from Scientific Reports
#320
of 4,061 outputs
Altmetric has tracked 24,637,659 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 134,452 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,290 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 4,061 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.