Title |
The emerging genomics and systems biology research lead to systems genomics studies
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Published in |
BMC Genomics, December 2014
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DOI | 10.1186/1471-2164-15-s11-i1 |
Pubmed ID | |
Authors |
Mary Qu Yang, Kenji Yoshigoe, William Yang, Weida Tong, Xiang Qin, A Keith Dunker, Zhongxue Chen, Hamid R Arbania, Jun S Liu, Andrzej Niemierko, Jack Y Yang |
Abstract |
Synergistically integrating multi-layer genomic data at systems level not only can lead to deeper insights into the molecular mechanisms related to disease initiation and progression, but also can guide pathway-based biomarker and drug target identification. With the advent of high-throughput next-generation sequencing technologies, sequencing both DNA and RNA has generated multi-layer genomic data that can provide DNA polymorphism, non-coding RNA, messenger RNA, gene expression, isoform and alternative splicing information. Systems biology on the other hand studies complex biological systems, particularly systematic study of complex molecular interactions within specific cells or organisms. Genomics and molecular systems biology can be merged into the study of genomic profiles and implicated biological functions at cellular or organism level. The prospectively emerging field can be referred to as systems genomics or genomic systems biology. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 5% |
Unknown | 18 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 37% |
Student > Ph. D. Student | 3 | 16% |
Other | 2 | 11% |
Professor | 1 | 5% |
Student > Master | 1 | 5% |
Other | 3 | 16% |
Unknown | 2 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 4 | 21% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Business, Management and Accounting | 2 | 11% |
Psychology | 2 | 11% |
Medicine and Dentistry | 2 | 11% |
Other | 3 | 16% |
Unknown | 4 | 21% |