Chapter title |
Biological Microarrays
|
---|---|
Chapter number | 3 |
Book title |
Biological Microarrays
|
Published in |
Methods in molecular biology, January 2011
|
DOI | 10.1007/978-1-59745-551-0_3 |
Pubmed ID | |
Book ISBNs |
978-1-934115-95-4, 978-1-59745-551-0
|
Authors |
Dmitriy V. Volokhov, Hyesuk Kong, Keith Herold, Vladimir E. Chizhikov, Avraham Rasooly, Volokhov, Dmitriy V., Kong, Hyesuk, Herold, Keith, Chizhikov, Vladimir E., Rasooly, Avraham |
Abstract |
Microarrays are spatially ordered arrays with ligands chemically immobilized in discrete spots on a solid matrix, usually a microscope slide. Microarrays are a high-throughput large-scale screening system enabling simultaneous identification of a large number of labeled target molecules (up to several hundred thousand) that bind specifically to the immobilized ligands of the array. DNA microarrays represent a promising tool for clinical, environmental, and industrial microbiology since the technology allows relatively rapid identification of large number of genetic determinants simultaneously, providing detailed genomic level information regarding the pathogen species, including identification of their virulence-associated factors and the presence of antibiotic resistance genes. In this chapter, we describe key aspects and methodologies important for the development and use of DNA microarrays for microbial diagnostics. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 54% |
Student > Ph. D. Student | 2 | 15% |
Professor > Associate Professor | 1 | 8% |
Unknown | 3 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 5 | 38% |
Immunology and Microbiology | 2 | 15% |
Biochemistry, Genetics and Molecular Biology | 1 | 8% |
Chemical Engineering | 1 | 8% |
Engineering | 1 | 8% |
Other | 0 | 0% |
Unknown | 3 | 23% |