Title |
Tapentadol extended release in the management of peripheral diabetic neuropathic pain
|
---|---|
Published in |
Therapeutics and Clinical Risk Management, January 2015
|
DOI | 10.2147/tcrm.s32193 |
Pubmed ID | |
Authors |
Nalini Vadivelu, Alice Kai, Benjamin Maslin, Gopal Kodumudi, Aron Legler, Jack M Berger |
Abstract |
Tapentadol, a μ-opioid agonist and norepinephrine reuptake inhibitor, has been found to be an effective medication for a wide variety of chronic pain conditions, including back pain, cancer-related pain, and arthritic pain. It has also been found to have fewer gastrointestinal side effects than more traditional opioid-based therapies. More recently, tapentadol extended release has been demonstrated to be effective in the management of painful diabetic neuropathy, an often debilitating condition affecting approximately one-third of all patients with diabetes. This review highlights the most up-to-date basic and clinical studies by focusing on the mechanisms of action of tapentadol and its clinical efficacy, especially with regard to painful diabetic neuropathy. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 25% |
Colombia | 1 | 13% |
United States | 1 | 13% |
Canada | 1 | 13% |
Australia | 1 | 13% |
Unknown | 2 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 88% |
Scientists | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 70 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 14% |
Researcher | 6 | 9% |
Student > Ph. D. Student | 6 | 9% |
Student > Doctoral Student | 6 | 9% |
Other | 5 | 7% |
Other | 17 | 24% |
Unknown | 20 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 34% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
Unspecified | 4 | 6% |
Nursing and Health Professions | 3 | 4% |
Immunology and Microbiology | 2 | 3% |
Other | 6 | 9% |
Unknown | 26 | 37% |