Title |
The SafeBoosC Phase II Randomised Clinical Trial: A Treatment Guideline for Targeted Near-Infrared-Derived Cerebral Tissue Oxygenation versus Standard Treatment in Extremely Preterm Infants
|
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Published in |
Neonatology, August 2013
|
DOI | 10.1159/000351346 |
Pubmed ID | |
Authors |
Adelina Pellicer, Gorm Greisen, Manon Benders, Olivier Claris, Eugene Dempsey, Monica Fumagally, Christian Gluud, Cornelia Hagmann, Lena Hellström-Westas, Simon Hyttel-Sorensen, Petra Lemmers, Gunnar Naulaers, Gerhard Pichler, Claudia Roll, Frank van Bel, Wim van Oeveren, Maria Skoog, Martin Wolf, Topun Austin |
Abstract |
Near-infrared spectroscopy-derived regional tissue oxygen saturation of haemoglobin (rStO2) reflects venous oxygen saturation. If cerebral metabolism is stable, rStO2 can be used as an estimate of cerebral oxygen delivery. The SafeBoosC phase II randomised clinical trial hypothesises that the burden of hypo- and hyperoxia can be reduced by the combined use of close monitoring of the cerebral rStO2 and a treatment guideline to correct deviations in rStO2 outside a predefined target range. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 144 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 19 | 13% |
Researcher | 18 | 12% |
Student > Master | 18 | 12% |
Other | 17 | 12% |
Student > Bachelor | 12 | 8% |
Other | 32 | 22% |
Unknown | 30 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 78 | 53% |
Engineering | 7 | 5% |
Agricultural and Biological Sciences | 5 | 3% |
Neuroscience | 5 | 3% |
Nursing and Health Professions | 4 | 3% |
Other | 12 | 8% |
Unknown | 35 | 24% |