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Safety of Daily Co-Trimoxazole in Pregnancy in an Area of Changing Malaria Epidemiology: A Phase 3b Randomized Controlled Clinical Trial

Overview of attention for article published in PLOS ONE, May 2014
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1 X user

Citations

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Title
Safety of Daily Co-Trimoxazole in Pregnancy in an Area of Changing Malaria Epidemiology: A Phase 3b Randomized Controlled Clinical Trial
Published in
PLOS ONE, May 2014
DOI 10.1371/journal.pone.0096017
Pubmed ID
Authors

Christine Manyando, Eric M. Njunju, David Mwakazanga, Gershom Chongwe, Rhoda Mkandawire, Davies Champo, Modest Mulenga, Maaike De Crop, Yves Claeys, Raffaella M. Ravinetto, Chantal van Overmeir, Umberto D’ Alessandro, Jean-Pierre Van geertruyden

Abstract

Antibiotic therapy during pregnancy may be beneficial and impacts positively on the reduction of adverse pregnancy outcomes. No studies have been done so far on the effects of daily Co-trimoxazole (CTX) prophylaxis on birth outcomes. A phase 3b randomized trial was conducted to establish that daily CTX in pregnancy is not inferior to SP intermittent preventive treatment (IPT) in reducing placental malaria; preventing peripheral parasitaemia; preventing perinatal mortality and also improving birth weight. To establish its safety on the offspring by measuring the gestational age and birth weight at delivery, and compare the safety and efficacy profile of CTX to that of SP.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
Ghana 1 <1%
Ethiopia 1 <1%
Australia 1 <1%
Peru 1 <1%
Unknown 172 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 33 19%
Researcher 23 13%
Student > Ph. D. Student 19 11%
Student > Doctoral Student 11 6%
Other 8 4%
Other 30 17%
Unknown 54 30%
Readers by discipline Count As %
Medicine and Dentistry 61 34%
Nursing and Health Professions 17 10%
Agricultural and Biological Sciences 11 6%
Biochemistry, Genetics and Molecular Biology 6 3%
Pharmacology, Toxicology and Pharmaceutical Science 6 3%
Other 22 12%
Unknown 55 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2015.
All research outputs
#20,249,662
of 22,778,347 outputs
Outputs from PLOS ONE
#173,506
of 194,344 outputs
Outputs of similar age
#192,822
of 226,993 outputs
Outputs of similar age from PLOS ONE
#4,020
of 4,670 outputs
Altmetric has tracked 22,778,347 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 194,344 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 4,670 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.