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X Demographics
Mendeley readers
Attention Score in Context
| Title |
An All-Atom Model of the Chromatin Fiber Containing Linker Histones Reveals a Versatile Structure Tuned by the Nucleosomal Repeat Length
|
|---|---|
| Published in |
PLOS ONE, September 2007
|
| DOI | 10.1371/journal.pone.0000877 |
| Pubmed ID | |
| Authors |
Hua Wong, Jean-Marc Victor, Julien Mozziconacci |
| Abstract |
In the nucleus of eukaryotic cells, histone proteins organize the linear genome into a functional and hierarchical architecture. In this paper, we use the crystal structures of the nucleosome core particle, B-DNA and the globular domain of H5 linker histone to build the first all-atom model of compact chromatin fibers. In this 3D jigsaw puzzle, DNA bending is achieved by solving an inverse kinematics problem. Our model is based on recent electron microscopy measurements of reconstituted fiber dimensions. Strikingly, we find that the chromatin fiber containing linker histones is a polymorphic structure. We show that different fiber conformations are obtained by tuning the linker histone orientation at the nucleosomes entry/exit according to the nucleosomal repeat length. We propose that the observed in vivo quantization of nucleosomal repeat length could reflect nature's ability to use the DNA molecule's helical geometry in order to give chromatin versatile topological and mechanical properties. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 2 | 40% |
| United States | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 3 | 60% |
| Members of the public | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 5% |
| Israel | 2 | 2% |
| France | 1 | <1% |
| Brazil | 1 | <1% |
| Sweden | 1 | <1% |
| Germany | 1 | <1% |
| United Kingdom | 1 | <1% |
| Chile | 1 | <1% |
| Russia | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 110 | 87% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 36 | 29% |
| Student > Ph. D. Student | 33 | 26% |
| Student > Master | 11 | 9% |
| Professor | 10 | 8% |
| Student > Postgraduate | 8 | 6% |
| Other | 16 | 13% |
| Unknown | 12 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 65 | 52% |
| Biochemistry, Genetics and Molecular Biology | 18 | 14% |
| Physics and Astronomy | 11 | 9% |
| Chemistry | 7 | 6% |
| Engineering | 3 | 2% |
| Other | 7 | 6% |
| Unknown | 15 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 November 2019.
All research outputs
#5,411,286
of 22,780,165 outputs
Outputs from PLOS ONE
#65,922
of 194,388 outputs
Outputs of similar age
#19,619
of 69,934 outputs
Outputs of similar age from PLOS ONE
#103
of 222 outputs
Altmetric has tracked 22,780,165 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 194,388 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 69,934 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 222 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.