↓ Skip to main content

Understanding alternative splicing: towards a cellular code

Overview of attention for article published in Nature Reviews Molecular Cell Biology, May 2005
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

patent
6 patents
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
883 Dimensions

Readers on

mendeley
1119 Mendeley
citeulike
21 CiteULike
connotea
3 Connotea
Title
Understanding alternative splicing: towards a cellular code
Published in
Nature Reviews Molecular Cell Biology, May 2005
DOI 10.1038/nrm1645
Pubmed ID
Authors

Arianne J. Matlin, Francis Clark, Christopher W. J. Smith

Abstract

In violation of the 'one gene, one polypeptide' rule, alternative splicing allows individual genes to produce multiple protein isoforms - thereby playing a central part in generating complex proteomes. Alternative splicing also has a largely hidden function in quantitative gene control, by targeting RNAs for nonsense-mediated decay. Traditional gene-by-gene investigations of alternative splicing mechanisms are now being complemented by global approaches. These promise to reveal details of the nature and operation of cellular codes that are constituted by combinations of regulatory elements in pre-mRNA substrates and by cellular complements of splicing regulators, which together determine regulated splicing pathways.

Mendeley readers

The data shown below were compiled from readership statistics for 1,119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 24 2%
United Kingdom 8 <1%
Germany 7 <1%
Spain 6 <1%
Canada 5 <1%
Chile 5 <1%
France 5 <1%
Italy 3 <1%
Portugal 3 <1%
Other 33 3%
Unknown 1020 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 342 31%
Researcher 214 19%
Student > Bachelor 134 12%
Student > Master 118 11%
Professor > Associate Professor 57 5%
Other 173 15%
Unknown 81 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 601 54%
Biochemistry, Genetics and Molecular Biology 221 20%
Medicine and Dentistry 62 6%
Computer Science 29 3%
Chemistry 25 2%
Other 84 8%
Unknown 97 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2018.
All research outputs
#1,236,923
of 13,366,062 outputs
Outputs from Nature Reviews Molecular Cell Biology
#361
of 2,016 outputs
Outputs of similar age
#29,278
of 278,790 outputs
Outputs of similar age from Nature Reviews Molecular Cell Biology
#14
of 40 outputs
Altmetric has tracked 13,366,062 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,016 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,790 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.