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Understanding alternative splicing: towards a cellular code

Overview of attention for article published in Nature Reviews Molecular Cell Biology, May 2005
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

patent
6 patents
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
942 Dimensions

Readers on

mendeley
1177 Mendeley
citeulike
21 CiteULike
connotea
3 Connotea
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Title
Understanding alternative splicing: towards a cellular code
Published in
Nature Reviews Molecular Cell Biology, May 2005
DOI 10.1038/nrm1645
Pubmed ID
Authors

Arianne J. Matlin, Francis Clark, Christopher W. J. Smith

Abstract

In violation of the 'one gene, one polypeptide' rule, alternative splicing allows individual genes to produce multiple protein isoforms - thereby playing a central part in generating complex proteomes. Alternative splicing also has a largely hidden function in quantitative gene control, by targeting RNAs for nonsense-mediated decay. Traditional gene-by-gene investigations of alternative splicing mechanisms are now being complemented by global approaches. These promise to reveal details of the nature and operation of cellular codes that are constituted by combinations of regulatory elements in pre-mRNA substrates and by cellular complements of splicing regulators, which together determine regulated splicing pathways.

Mendeley readers

The data shown below were compiled from readership statistics for 1,177 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 23 2%
United Kingdom 8 <1%
Germany 7 <1%
Spain 6 <1%
Canada 5 <1%
Chile 5 <1%
France 5 <1%
Italy 3 <1%
Portugal 3 <1%
Other 32 3%
Unknown 1080 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 359 31%
Researcher 218 19%
Student > Bachelor 142 12%
Student > Master 126 11%
Student > Doctoral Student 56 5%
Other 183 16%
Unknown 93 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 604 51%
Biochemistry, Genetics and Molecular Biology 254 22%
Medicine and Dentistry 63 5%
Computer Science 32 3%
Chemistry 27 2%
Other 86 7%
Unknown 111 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2018.
All research outputs
#1,812,038
of 17,363,630 outputs
Outputs from Nature Reviews Molecular Cell Biology
#502
of 2,246 outputs
Outputs of similar age
#32,647
of 296,727 outputs
Outputs of similar age from Nature Reviews Molecular Cell Biology
#14
of 39 outputs
Altmetric has tracked 17,363,630 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,246 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.3. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 296,727 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.