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Serotonylation of Vascular Proteins Important to Contraction

Overview of attention for article published in PLOS ONE, May 2009
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Title
Serotonylation of Vascular Proteins Important to Contraction
Published in
PLOS ONE, May 2009
DOI 10.1371/journal.pone.0005682
Pubmed ID
Authors

Stephanie W. Watts, Jessica R. C. Priestley, Janice M. Thompson

Abstract

Serotonin (5-hydroxytryptamine, 5-HT) was named for its source (sero-) and ability to modify smooth muscle tone (tonin). The biological effects of 5-HT are believed to be carried out by stimulation of serotonin receptors at the plasma membrane. Serotonin has recently been shown to be synthesized in vascular smooth muscle and taken up from external sources, placing 5-HT inside the cell. The enzyme transglutaminase uses primary amines such as 5-HT to covalently modify proteins on glutamine residues. We tested the hypothesis that 5-HT is a substrate for transglutaminase in arterial vascular smooth muscle, with protein serotonylation having physiological function.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Russia 1 1%
Canada 1 1%
Unknown 77 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 20%
Researcher 13 16%
Student > Bachelor 11 14%
Student > Master 10 12%
Professor 4 5%
Other 14 17%
Unknown 13 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 38%
Biochemistry, Genetics and Molecular Biology 8 10%
Medicine and Dentistry 6 7%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Neuroscience 3 4%
Other 12 15%
Unknown 16 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2017.
All research outputs
#7,451,584
of 22,780,967 outputs
Outputs from PLOS ONE
#88,687
of 194,391 outputs
Outputs of similar age
#36,865
of 108,417 outputs
Outputs of similar age from PLOS ONE
#252
of 493 outputs
Altmetric has tracked 22,780,967 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 194,391 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,417 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 493 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.