https://t.co/B3CbH6t5aB "The decreased plasma levels of BCAA may correspond to a critical need for Krebs cycle energy substrates in the brain that increased metabolism in the periphery is trying to provide."
3,675 followers
3,675 followers
https://t.co/B3CbH6t5aB "Therefore, early weight loss in HD is associated with a systemic metabolic defect, and BCAA levels may be used as a biomarker, indicative of disease onset and early progression."
3,675 followers
https://t.co/B3CbH6t5aB "BCAA levels were correlated with weight loss and, importantly, with disease progression and abnormal triplet repeat expansion size in the HD1 gene." "Levels of IGF1, which is regulated by BCAA, were also significantly lower in th
3,675 followers
https://t.co/B3CbH6t5aB "This distinction was attributable to low levels of the branched chain amino acids (BCAA), valine, leucine and isoleucine."