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Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice

Overview of attention for article published in BMC Genomics, December 2007
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Title
Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice
Published in
BMC Genomics, December 2007
DOI 10.1186/1471-2164-8-452
Pubmed ID
Authors

Nicolas F Delahaye, Nicolas Coltel, Denis Puthier, Mathieu Barbier, Philippe Benech, Florence Joly, Fuad A Iraqi, Georges E Grau, Catherine Nguyen, Pascal Rihet

Abstract

Microarray analyses allow the identification and assessment of molecular signatures in whole tissues undergoing pathological processes. To better understand cerebral malaria pathogenesis, we investigated intra-cerebral gene-expression profiles in well-defined genetically cerebral malaria-resistant (CM-R) and CM-susceptible (CM-S) mice, upon infection by Plasmodium berghei ANKA (PbA). We investigated mouse transcriptional responses at early and late stages of infection by use of cDNA microarrays.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 2 5%
Kenya 1 2%
France 1 2%
Unknown 40 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 30%
Student > Master 8 18%
Researcher 5 11%
Professor 3 7%
Student > Doctoral Student 3 7%
Other 8 18%
Unknown 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 48%
Biochemistry, Genetics and Molecular Biology 6 14%
Immunology and Microbiology 3 7%
Medicine and Dentistry 2 5%
Neuroscience 2 5%
Other 4 9%
Unknown 6 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2014.
All research outputs
#7,451,584
of 22,780,967 outputs
Outputs from BMC Genomics
#3,595
of 10,643 outputs
Outputs of similar age
#41,199
of 155,839 outputs
Outputs of similar age from BMC Genomics
#24
of 87 outputs
Altmetric has tracked 22,780,967 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,643 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 155,839 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.