Title |
Baseline Mobility is Not Associated with Decline in Cognitive Function in Healthy Community-Dwelling Older Adults: Findings From The Irish Longitudinal Study on Ageing (TILDA)
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Published in |
American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry, November 2017
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DOI | 10.1016/j.jagp.2017.11.006 |
Pubmed ID | |
Authors |
Orna Donoghue, Joanne Feeney, Neil O'Leary, Rose Anne Kenny |
Abstract |
Few studies examine the relationship between Timed Up-and-Go (TUG), a commonly used clinical test, and cognitive decline. This study examines whether TUG, usual gait speed (UGS), and dual-task gait speed (DTGS) predict decline in global cognition, executive function, processing speed, memory, and attention with follow-up of up to 5.9 years. Longitudinal study. The Irish Longitudinal Study on Ageing (TILDA), a nationally representative cohort study. Community-dwelling adults aged ≥65 years, with Mini-Mental State Examination (MMSE) score ≥18 and no known history of memory impairment, dementia, Alzheimer's disease or Parkinson's disease were included (N = 2,250). Participants completed mobility tasks during the baseline health assessment and cognitive tasks during interviews conducted at 2 year intervals (waves 1, 2, and 3) and health assessments (waves 1 and 3). Linear and Poisson mixed effects regression models were used to examine longitudinal associations between mobility and each cognitive test, adjusting for sociodemographics and physical and mental health. There was little evidence of an association between TUG, UGS, or DTGS with decline in cognitive function after adjusting for confounders. These mobility tasks are not sensitive predictors of cognitive decline in this high-functioning, community-dwelling sample; nonetheless, limited decline in cognitive function was observed during follow-up. Further work with longer follow-up and/or analysis of more specific and comprehensive measures associated with gait is required. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 107 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 20 | 19% |
Student > Master | 16 | 15% |
Student > Bachelor | 13 | 12% |
Researcher | 9 | 8% |
Student > Doctoral Student | 6 | 6% |
Other | 7 | 7% |
Unknown | 36 | 34% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 17% |
Psychology | 17 | 16% |
Neuroscience | 9 | 8% |
Nursing and Health Professions | 6 | 6% |
Sports and Recreations | 3 | 3% |
Other | 14 | 13% |
Unknown | 40 | 37% |