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Mendeley readers
Attention Score in Context
| Title |
Midbrain circuits that set locomotor speed and gait selection
|
|---|---|
| Published in |
Nature, January 2018
|
| DOI | 10.1038/nature25448 |
| Pubmed ID | |
| Authors |
V. Caggiano, R. Leiras, H. Goñi-Erro, D. Masini, C. Bellardita, J. Bouvier, V. Caldeira, G. Fisone, O. Kiehn |
| Abstract |
Locomotion is a fundamental motor function common to the animal kingdom. It is implemented episodically and adapted to behavioural needs, including exploration, which requires slow locomotion, and escape behaviour, which necessitates faster speeds. The control of these functions originates in brainstem structures, although the neuronal substrate(s) that support them have not yet been elucidated. Here we show in mice that speed and gait selection are controlled by glutamatergic excitatory neurons (GlutNs) segregated in two distinct midbrain nuclei: the cuneiform nucleus (CnF) and the pedunculopontine nucleus (PPN). GlutNs in both of these regions contribute to the control of slower, alternating-gait locomotion, whereas only GlutNs in the CnF are able to elicit high-speed, synchronous-gait locomotion. Additionally, both the activation dynamics and the input and output connectivity matrices of GlutNs in the PPN and the CnF support explorative and escape locomotion, respectively. Our results identify two regions in the midbrain that act in conjunction to select context-dependent locomotor behaviours. |
X Demographics
The data shown below were collected from the profiles of 97 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 21 | 22% |
| United Kingdom | 7 | 7% |
| Denmark | 4 | 4% |
| Japan | 3 | 3% |
| Canada | 3 | 3% |
| Australia | 2 | 2% |
| Ireland | 2 | 2% |
| Brazil | 1 | 1% |
| Switzerland | 1 | 1% |
| Other | 8 | 8% |
| Unknown | 45 | 46% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 68 | 70% |
| Scientists | 25 | 26% |
| Practitioners (doctors, other healthcare professionals) | 3 | 3% |
| Science communicators (journalists, bloggers, editors) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 550 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 550 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 116 | 21% |
| Researcher | 108 | 20% |
| Student > Master | 51 | 9% |
| Student > Bachelor | 36 | 7% |
| Student > Doctoral Student | 31 | 6% |
| Other | 105 | 19% |
| Unknown | 103 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 222 | 40% |
| Agricultural and Biological Sciences | 83 | 15% |
| Medicine and Dentistry | 35 | 6% |
| Engineering | 21 | 4% |
| Biochemistry, Genetics and Molecular Biology | 15 | 3% |
| Other | 63 | 11% |
| Unknown | 111 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 139. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2023.
All research outputs
#304,470
of 25,791,949 outputs
Outputs from Nature
#16,429
of 98,793 outputs
Outputs of similar age
#6,937
of 454,013 outputs
Outputs of similar age from Nature
#320
of 842 outputs
Altmetric has tracked 25,791,949 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 98,793 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 102.7. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 454,013 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 842 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.