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Attention Score in Context
| Title |
Aptamer selection and applications for breast cancer diagnostics and therapy
|
|---|---|
| Published in |
Journal of Nanobiotechnology, November 2017
|
| DOI | 10.1186/s12951-017-0311-4 |
| Pubmed ID | |
| Authors |
Mei Liu, Xiaocheng Yu, Zhu Chen, Tong Yang, Dandan Yang, Qianqian Liu, Keke Du, Bo Li, Zhifei Wang, Song Li, Yan Deng, Nongyue He |
| Abstract |
Aptamers are short non-coding, single-stranded oligonucleotides (RNA or DNA) developed through Systematic Evolution of Ligands by Exponential enrichment (SELEX) in vitro. Similar to antibodies, aptamers can bind to specific targets with high affinity, and are considered promising therapeutic agents as they have several advantages over antibodies, including high specificity, stability, and non-immunogenicity. Furthermore, aptamers can be produced at a low cost and easily modified, and are, therefore, called "chemical antibodies". In the past years, a variety of aptamers specifically bound to both breast cancer biomarkers and cells had been selected. Besides, taking advantage of nanomaterials, there were a number of aptamer-nanomaterial conjugates been developed and widely investigated for diagnostics and targeted therapy of breast cancer. In this short review, we first present a systematical review of various aptamer selection methods. Then, various aptamer-based diagnostic and therapeutic strategies of breast cancer were provided. Finally, the current problems, challenges, and future perspectives in the field were thoroughly discussed. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| China | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 146 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 23% |
| Student > Master | 15 | 10% |
| Researcher | 14 | 10% |
| Student > Bachelor | 11 | 8% |
| Student > Doctoral Student | 9 | 6% |
| Other | 17 | 12% |
| Unknown | 47 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 31 | 21% |
| Chemistry | 19 | 13% |
| Materials Science | 8 | 5% |
| Engineering | 7 | 5% |
| Medicine and Dentistry | 6 | 4% |
| Other | 20 | 14% |
| Unknown | 55 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2019.
All research outputs
#14,373,275
of 23,016,919 outputs
Outputs from Journal of Nanobiotechnology
#513
of 1,438 outputs
Outputs of similar age
#180,981
of 325,979 outputs
Outputs of similar age from Journal of Nanobiotechnology
#7
of 13 outputs
Altmetric has tracked 23,016,919 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,438 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,979 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.