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High efficacy of (Z)-γ-bisabolene from the essential oil of Galinsoga parviflora (Asteraceae) as larvicide and oviposition deterrent against six mosquito vectors

Overview of attention for article published in Environmental Science and Pollution Research, January 2018
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Title
High efficacy of (Z)-γ-bisabolene from the essential oil of Galinsoga parviflora (Asteraceae) as larvicide and oviposition deterrent against six mosquito vectors
Published in
Environmental Science and Pollution Research, January 2018
DOI 10.1007/s11356-018-1203-3
Pubmed ID
Authors

Marimuthu Govindarajan, Baskaralingam Vaseeharan, Naiyf S. Alharbi, Shine Kadaikunnan, Jamal M. Khaled, Mohammed N. Al-anbr, Sami A. Alyahya, Filippo Maggi, Giovanni Benelli

Abstract

The eco-friendly management of mosquitoes with novel and effective larvicides and oviposition deterrents is a crucial challenge to prevent outbreaks of mosquito-borne diseases. However, most of the herbal formulations tested in these years showed LC50 values higher of 40 ppm, and significant oviposition deterrent activity only when tested at relatively higher doses (> 50 μg/ml). Herein, we studied the chemical composition of the Galinsoga parviflora essential oil (EO). This plant is an annual herb native to South America naturalized all over the world. We tested the EO larvicidal and oviposition deterrent action on 6 mosquito species. Totally 37 compounds were identified in the EO of G. parviflora by GC and GC-MS analyses. The major constituent was (Z)-γ-bisabolene (38.9%). The G. parviflora EO and (Z)-γ-bisabolene showed acute toxicity on An. stephensi (LC50 = 31.04 and 2.04 μg/ml, respectively), Ae. aegypti (LC50 = 34.22 and 2.26 μg/ml, respectively), Cx. quinquefasciatus (LC50 = 37.10 and 2.47 μg/ml, respectively), An. subpictus (LC50 = 40.97 and 4.09 μg/ml, respectively), Ae. albopictus (LC50 = 45.55 and 4.50 μg/ml, respectively) and Cx. tritaeniorhynchus (LC50 = 49.56 and 4.87 μg/ml, respectively) larvae. Furthermore, the oviposition deterrent potential of the G. parviflora EO and (Z)-γ-bisabolene was studied on six mosquito vectors, showing that 25 μg/ml of (Z)-γ-bisabolene led to an Oviposition Activity Index lower of - 0.79 in all tested mosquito vectors. Overall, all larvicidal LC50 values estimated for (Z)-γ-bisabolene were lower than 5 μg/ml. This result far encompasses current evidences of toxicity reported for the large majority of botanical products currently tested against mosquito young instars, allowing us to propose this compound as an highly effective mosquito larvicide and oviposition deterrent.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 17%
Student > Master 10 17%
Student > Ph. D. Student 7 12%
Student > Doctoral Student 5 8%
Student > Bachelor 4 7%
Other 14 23%
Unknown 10 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 28%
Chemistry 8 13%
Medicine and Dentistry 6 10%
Immunology and Microbiology 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Other 10 17%
Unknown 13 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2018.
All research outputs
#21,420,714
of 23,911,072 outputs
Outputs from Environmental Science and Pollution Research
#7,000
of 9,883 outputs
Outputs of similar age
#385,035
of 447,384 outputs
Outputs of similar age from Environmental Science and Pollution Research
#165
of 219 outputs
Altmetric has tracked 23,911,072 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,883 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,384 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 219 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.