Chapter title |
Assessment of Placental Transport Function in Studies of Disease Programming
|
---|---|
Chapter number | 14 |
Book title |
Investigations of Early Nutrition Effects on Long-Term Health
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7614-0_14 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7613-3, 978-1-4939-7614-0
|
Authors |
Amanda N. Sferruzzi-Perri, Sferruzzi-Perri, Amanda |
Abstract |
Environmental conditions during pregnancy affect fetal growth and development and program the offspring for poor future health. These effects may be mediated by the placenta, which develops to transfer nutrients from the mother to the fetus for growth. The ability to measure the unidirectional maternofetal transfer of non-metabolizable radio-analogues of glucose and amino acid by the placenta in vivo has thus been invaluable to our understanding of the regulation of fetal growth, particularly in small animal models. Herein, I describe the method by which in vivo placental transfer function can be quantified in the mouse, an animal model widely used in studies of in utero disease programming. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 3 | 27% |
Researcher | 2 | 18% |
Student > Bachelor | 2 | 18% |
Student > Doctoral Student | 1 | 9% |
Other | 1 | 9% |
Other | 1 | 9% |
Unknown | 1 | 9% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 4 | 36% |
Medicine and Dentistry | 3 | 27% |
Agricultural and Biological Sciences | 1 | 9% |
Computer Science | 1 | 9% |
Unknown | 2 | 18% |