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Mendeley readers
Attention Score in Context
| Title |
Role of Histone Tails in Structural Stability of the Nucleosome
|
|---|---|
| Published in |
PLoS Computational Biology, December 2011
|
| DOI | 10.1371/journal.pcbi.1002279 |
| Pubmed ID | |
| Authors |
Mithun Biswas, Karine Voltz, Jeremy C. Smith, Jörg Langowski |
| Abstract |
Histone tails play an important role in nucleosome structure and dynamics. Here we investigate the effect of truncation of histone tails H3, H4, H2A and H2B on nucleosome structure with 100 ns all-atom molecular dynamics simulations. Tail domains of H3 and H2B show propensity of α-helics formation during the intact nucleosome simulation. On truncation of H4 or H2B tails no structural change occurs in histones. However, H3 or H2A tail truncation results in structural alterations in the histone core domain, and in both the cases the structural change occurs in the H2Aα3 domain. We also find that the contacts between the histone H2A C terminal docking domain and surrounding residues are destabilized upon H3 tail truncation. The relation between the present observations and corresponding experiments is discussed. |
Mendeley readers
The data shown below were compiled from readership statistics for 206 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Germany | 2 | <1% |
| Italy | 1 | <1% |
| South Africa | 1 | <1% |
| United Kingdom | 1 | <1% |
| Israel | 1 | <1% |
| Japan | 1 | <1% |
| Luxembourg | 1 | <1% |
| Unknown | 195 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 72 | 35% |
| Researcher | 30 | 15% |
| Student > Master | 25 | 12% |
| Student > Bachelor | 15 | 7% |
| Student > Doctoral Student | 10 | 5% |
| Other | 20 | 10% |
| Unknown | 34 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 74 | 36% |
| Biochemistry, Genetics and Molecular Biology | 60 | 29% |
| Chemistry | 15 | 7% |
| Engineering | 6 | 3% |
| Physics and Astronomy | 4 | 2% |
| Other | 8 | 4% |
| Unknown | 39 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 January 2022.
All research outputs
#8,745,608
of 25,887,951 outputs
Outputs from PLoS Computational Biology
#5,699
of 9,065 outputs
Outputs of similar age
#73,885
of 251,418 outputs
Outputs of similar age from PLoS Computational Biology
#45
of 116 outputs
Altmetric has tracked 25,887,951 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,065 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.3. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,418 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.