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The “portrait” of hereditary breast cancer

Overview of attention for article published in Breast Cancer Research and Treatment, February 2005
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4 Wikipedia pages

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42 Mendeley
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1 CiteULike
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Title
The “portrait” of hereditary breast cancer
Published in
Breast Cancer Research and Treatment, February 2005
DOI 10.1007/s10549-004-2172-4
Pubmed ID
Authors

Marc Lacroix, Guy Leclercq

Abstract

Five to ten per cent of all breast carcinomas are of hereditary origin. Many of them have been associated to mutations in the BRCA1 and BRCA2 susceptibility genes. No "BRCA3" gene has been found to account for the non-BRCA1/BRCA2 breast cancer (BRCAx) families, and BRCAx tumors are increasingly believed to originate from multiple distinct genetic events. Phenotype studies have questioned the existence of specific "portraits" among hereditary breast carcinomas (HBC). They have shown that most BRCA1 tumors have a "basal (epithelial)-like" aspect, while BRCA2 and BRCAx HBC are more heterogeneous. HBC have also been submitted to genetic analyses, notably with the objective of resolving the heterogeneity of BRCAx lesions. The present review aims to summarize recent data on BRCA1, BRCA2, and BRCAx HBC, including hypotheses on the origin of BRCA1 tumors and their paradoxical relations to estrogen-sensitivity.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Germany 1 2%
Unknown 40 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 40%
Student > Master 6 14%
Professor 3 7%
Student > Ph. D. Student 3 7%
Student > Postgraduate 2 5%
Other 4 10%
Unknown 7 17%
Readers by discipline Count As %
Medicine and Dentistry 12 29%
Biochemistry, Genetics and Molecular Biology 9 21%
Agricultural and Biological Sciences 7 17%
Computer Science 2 5%
Unspecified 1 2%
Other 3 7%
Unknown 8 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2021.
All research outputs
#7,452,489
of 22,783,848 outputs
Outputs from Breast Cancer Research and Treatment
#1,657
of 4,654 outputs
Outputs of similar age
#36,515
of 141,285 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#10
of 23 outputs
Altmetric has tracked 22,783,848 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,654 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,285 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.