Title |
Human cytomegalovirus infection and coronary heart disease: a systematic review
|
---|---|
Published in |
Virology Journal, February 2018
|
DOI | 10.1186/s12985-018-0937-3 |
Pubmed ID | |
Authors |
Yu Du, Guangxue Zhang, Zhijun Liu |
Abstract |
Human cytomegalovirus (HCMV) infection is closely associated with coronary heart disease. In 1987, Adam et al. were the first to report an association between HCMV infection and atherosclerosis (AS), and later, many serum epidemiology and molecular biology studies showed that HCMV-infected endothelial cells play an important role in the development of AS. As patients with HCMV are generally susceptible to coronary heart disease, and with the increasing elderly population, a review of recent studies focusing on the relationships of HCMV infection and coronary heart disease is timely and necessary. The role of HCMV infection in the development of AS needs further study, since many remaining issues need to be explored and resolved. For example, whether HCMV promotes the development of coronary AS, and what the independent factors that lead to coronary artery AS by viral infection are. A comprehensive understanding of HCMV infection is needed in order to develop better strategies for preventing AS. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 18% |
India | 1 | 9% |
Armenia | 1 | 9% |
Spain | 1 | 9% |
Mexico | 1 | 9% |
Unknown | 5 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 82% |
Scientists | 1 | 9% |
Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 75 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 15% |
Student > Ph. D. Student | 8 | 11% |
Researcher | 6 | 8% |
Student > Master | 5 | 7% |
Student > Doctoral Student | 2 | 3% |
Other | 10 | 13% |
Unknown | 33 | 44% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 12 | 16% |
Medicine and Dentistry | 10 | 13% |
Agricultural and Biological Sciences | 8 | 11% |
Immunology and Microbiology | 5 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 5 | 7% |
Unknown | 33 | 44% |