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Antidepressants use and risk of cataract development: a systematic review and meta-analysis

Overview of attention for article published in BMC Ophthalmology, February 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

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1 Redditor

Citations

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Title
Antidepressants use and risk of cataract development: a systematic review and meta-analysis
Published in
BMC Ophthalmology, February 2018
DOI 10.1186/s12886-018-0699-0
Pubmed ID
Authors

Yana Fu, Qi Dai, Liwei Zhu, Shuangqing Wu

Abstract

Epidemiological studies suggest that antidepressants use may increase the risk of cataract, but the results are inconclusive. We aimed to examine this association by performing a systematic review and meta-analysis. Relevant studies were identified by searching PubMed and Web of Science databases through June 2017. We included studies that reported risk estimates for the association between antidepressants use and cataract risk. A random-effects model was used to calculate the summary odds ratio (OR) with its 95% confidence interval (CI). We identified seven studies of antidepressants use and risk of cataract involving 447,672 cases and 1,510,391 controls. Overall, the combined ORs (95% CIs) of cataract for selective serotonin reuptake inhibitors (SSRIs), serotonin noradrenalin reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs) were 1.12 (1.06-1.19), 1.13 (1.04-1.24), and 1.19 (1.11-1.28), respectively. A certain degree of heterogeneity was observed across studies (P < 0.001, I 2  = 92.2% for SSRIs, P = 0.026, I 2  = 67.5% for SNRIs, and P = 0.092, I 2  = 58.0% for TCAs). This meta-analysis provides evidence of a significant positive association between antidepressants use and risk of cataract. Because of the heterogeneity and limited eligible studies, further prospective studies are warranted to confirm the preliminary findings of our study.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 13%
Student > Bachelor 3 9%
Researcher 2 6%
Student > Ph. D. Student 2 6%
Student > Doctoral Student 1 3%
Other 5 16%
Unknown 15 47%
Readers by discipline Count As %
Medicine and Dentistry 6 19%
Biochemistry, Genetics and Molecular Biology 3 9%
Nursing and Health Professions 2 6%
Agricultural and Biological Sciences 2 6%
Psychology 1 3%
Other 3 9%
Unknown 15 47%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 March 2019.
All research outputs
#5,738,950
of 23,881,329 outputs
Outputs from BMC Ophthalmology
#268
of 2,554 outputs
Outputs of similar age
#111,553
of 441,534 outputs
Outputs of similar age from BMC Ophthalmology
#7
of 41 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,554 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 441,534 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.