↓ Skip to main content

Stress-induced plasticity of dynamic collagen networks

Overview of attention for article published in Nature Communications, October 2017
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
117 Dimensions

Readers on

mendeley
48 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Stress-induced plasticity of dynamic collagen networks
Published in
Nature Communications, October 2017
DOI 10.1038/s41467-017-01011-7
Pubmed ID
Authors

Jihan Kim, Jingchen Feng, Christopher A. R. Jones, Xiaoming Mao, Leonard M. Sander, Herbert Levine, Bo Sun

Abstract

The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells, and at the same time regulate many important cellular functions such as migration, differentiation, and growth. Here we show that 3D collagen gels, major components of connective tissues and extracellular matrix (ECM), are significantly and irreversibly remodeled by cellular traction forces, as well as by macroscopic strains. To understand this ECM plasticity, we develop a computational model that takes into account the sliding and merging of ECM fibers. We have confirmed the model predictions with experiment. Our results suggest the profound impacts of cellular traction forces on their host ECM during development and cancer progression, and suggest indirect mechanical channels of cell-cell communications in 3D fibrous matrices.The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells. Here the authors show that 3D collagen gels, major components of connective tissues and extracellular matrix, are significantly and irreversibly remodelled by cellular traction forces and by macroscopic strains.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 19%
Student > Master 8 17%
Researcher 7 15%
Professor 6 13%
Other 2 4%
Other 5 10%
Unknown 11 23%
Readers by discipline Count As %
Engineering 7 15%
Biochemistry, Genetics and Molecular Biology 6 13%
Physics and Astronomy 6 13%
Chemistry 4 8%
Materials Science 4 8%
Other 9 19%
Unknown 12 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2022.
All research outputs
#18,410,971
of 22,805,349 outputs
Outputs from Nature Communications
#44,069
of 46,954 outputs
Outputs of similar age
#247,510
of 323,551 outputs
Outputs of similar age from Nature Communications
#1,287
of 1,363 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 46,954 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.6. This one is in the 2nd percentile – i.e., 2% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,551 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,363 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.