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Correlation Between Quorum Sensing Signal Molecules and Pseudomonas aeruginosa’s Biofilm Development and Virulency

Overview of attention for article published in Current Microbiology, February 2018
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  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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Title
Correlation Between Quorum Sensing Signal Molecules and Pseudomonas aeruginosa’s Biofilm Development and Virulency
Published in
Current Microbiology, February 2018
DOI 10.1007/s00284-018-1449-5
Pubmed ID
Authors

Abayomi Babatunde Alayande, Mar Mar Aung, In S. Kim

Abstract

Bacteria, when adhered to a substratum, can form biofilms. Nevertheless, many factors dictate biofilm formation and virulence factor production, including a response by the bacteria to their surroundings. This system is referred to as Quorum sensing (QS) also known as cell-cell communication. Pseudomonas aeruginosa is an infection causing agent in immune-compromised patients, it uses acyl-homoserine lactone (AHL) to coordinate its QS systems. In this work, the connection between some members of AHL produced by P. aeruginosa PAO1 and its biofilm development and the production of virulence factor was investigated. It was discovered that N-butanoyl-homoserine lactone (C4-HSL) and N-hexanoyl-L-homoserine lactone (C6-HSL) perform a more consequential and eminent function in the biofilm maturation and virulence factor production while N-(3-oxododecanoyl)-L-homoserine lactone (3OC12-HSL) plays a role in biofilm initiation. Because QS has been reported to be required for biofilm development and pathogenesis of P. aeruginosa, the results of this work have great importance and significance for the design of strategies for the control and prevention of biofilms.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 92 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 15%
Student > Master 12 13%
Researcher 10 11%
Student > Doctoral Student 8 9%
Student > Bachelor 8 9%
Other 12 13%
Unknown 28 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 18%
Agricultural and Biological Sciences 10 11%
Chemistry 7 8%
Immunology and Microbiology 5 5%
Medicine and Dentistry 5 5%
Other 16 17%
Unknown 32 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2018.
All research outputs
#13,064,572
of 23,023,224 outputs
Outputs from Current Microbiology
#1,159
of 2,426 outputs
Outputs of similar age
#208,645
of 442,600 outputs
Outputs of similar age from Current Microbiology
#20
of 48 outputs
Altmetric has tracked 23,023,224 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,426 research outputs from this source. They receive a mean Attention Score of 3.2. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,600 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.