Accumulation of the solvent vehicle sulphobutylether beta cyclodextrin sodium in critically ill patients treated with intravenous voriconazole under renal replacement therapy
Marc A von Mach, Jürgen Burhenne, Ludwig S Weilemann
Abstract
Voriconazole was introduced for the treatment of life-threatening fungal infections. The intravenous form includes the solvent vehicle sulphobutylether beta cyclodextrin sodium which shows an impaired clearance under intermittent dialysis therapy. This investigation aimed to determine first clinical data on sulphobutylether beta cyclodextrin sodium blood levels to verify the risk for accumulation.
Pharmacology, Toxicology and Pharmaceutical Science
11
26%
Agricultural and Biological Sciences
4
10%
Chemistry
3
7%
Psychology
1
2%
Other
0
0%
Unknown
9
21%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2023.
All research outputs
#6,846,906
of 24,814,419 outputs
Outputs from BMC Clinical Pharmacology
#26
of 59 outputs
Outputs of similar age
#24,687
of 80,610 outputs
Outputs of similar age from BMC Clinical Pharmacology
#2
of 2 outputs
Altmetric has tracked 24,814,419 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 59 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 80,610 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.
