Title |
APPLaUD: access for patients and participants to individual level uninterpreted genomic data
|
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Published in |
Human Genomics, February 2018
|
DOI | 10.1186/s40246-018-0139-5 |
Pubmed ID | |
Authors |
Adrian Thorogood, Jason Bobe, Barbara Prainsack, Anna Middleton, Erick Scott, Sarah Nelson, Manuel Corpas, Natasha Bonhomme, Laura Lyman Rodriguez, Madeleine Murtagh, Erika Kleiderman, on behalf of the Participant Values Task Team of the Global Alliance for Genomics and Health |
Abstract |
There is a growing support for the stance that patients and research participants should have better and easier access to their raw (uninterpreted) genomic sequence data in both clinical and research contexts. We review legal frameworks and literature on the benefits, risks, and practical barriers of providing individuals access to their data. We also survey genomic sequencing initiatives that provide or plan to provide individual access. Many patients and research participants expect to be able to access their health and genomic data. Individuals have a legal right to access their genomic data in some countries and contexts. Moreover, increasing numbers of participatory research projects, direct-to-consumer genetic testing companies, and now major national sequencing initiatives grant individuals access to their genomic sequence data upon request. Drawing on current practice and regulatory analysis, we outline legal, ethical, and practical guidance for genomic sequencing initiatives seeking to offer interested patients and participants access to their raw genomic data. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 16 | 33% |
Canada | 5 | 10% |
United States | 3 | 6% |
France | 2 | 4% |
South Africa | 1 | 2% |
Netherlands | 1 | 2% |
Colombia | 1 | 2% |
Central African Republic | 1 | 2% |
Comoros | 1 | 2% |
Other | 4 | 8% |
Unknown | 14 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 25 | 51% |
Members of the public | 20 | 41% |
Practitioners (doctors, other healthcare professionals) | 2 | 4% |
Science communicators (journalists, bloggers, editors) | 2 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 86 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 19% |
Student > Master | 10 | 12% |
Other | 8 | 9% |
Student > Bachelor | 8 | 9% |
Student > Ph. D. Student | 7 | 8% |
Other | 19 | 22% |
Unknown | 18 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 19% |
Biochemistry, Genetics and Molecular Biology | 15 | 17% |
Social Sciences | 10 | 12% |
Agricultural and Biological Sciences | 5 | 6% |
Computer Science | 4 | 5% |
Other | 14 | 16% |
Unknown | 22 | 26% |