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The Vpr protein from HIV-1: distinct roles along the viral life cycle

Overview of attention for article published in Retrovirology, February 2005
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (65th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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1 X user
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27 Wikipedia pages

Citations

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116 Dimensions

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200 Mendeley
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1 Connotea
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Title
The Vpr protein from HIV-1: distinct roles along the viral life cycle
Published in
Retrovirology, February 2005
DOI 10.1186/1742-4690-2-11
Pubmed ID
Authors

Erwann Le Rouzic, Serge Benichou

Abstract

The genomes of human and simian immunodeficiency viruses (HIV and SIV) encode the gag, pol and env genes and contain at least six supplementary open reading frames termed tat, rev, nef, vif, vpr, vpx and vpu. While the tat and rev genes encode regulatory proteins absolutely required for virus replication, nef, vif, vpr, vpx and vpu encode for small proteins referred to "auxiliary" (or "accessory"), since their expression is usually dispensable for virus growth in many in vitro systems. However, these auxiliary proteins are essential for viral replication and pathogenesis in vivo. The two vpr- and vpx-related genes are found only in members of the HIV-2/SIVsm/SIVmac group, whereas primate lentiviruses from other lineages (HIV-1, SIVcpz, SIVagm, SIVmnd and SIVsyk) contain a single vpr gene. In this review, we will mainly focus on vpr from HIV-1 and discuss the most recent developments in our understanding of Vpr functions and its role during the virus replication cycle.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 200 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 3%
South Africa 4 2%
Germany 1 <1%
Italy 1 <1%
Canada 1 <1%
India 1 <1%
Unknown 187 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 55 28%
Researcher 41 21%
Student > Master 23 12%
Student > Bachelor 15 8%
Student > Postgraduate 11 6%
Other 30 15%
Unknown 25 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 91 46%
Biochemistry, Genetics and Molecular Biology 33 17%
Medicine and Dentistry 18 9%
Immunology and Microbiology 12 6%
Chemistry 5 3%
Other 16 8%
Unknown 25 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2024.
All research outputs
#8,069,539
of 24,931,592 outputs
Outputs from Retrovirology
#421
of 1,142 outputs
Outputs of similar age
#24,405
of 71,725 outputs
Outputs of similar age from Retrovirology
#3
of 6 outputs
Altmetric has tracked 24,931,592 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 1,142 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 71,725 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.