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Mendeley readers
Attention Score in Context
| Title |
The thiazide-sensitive Na+-Cl− cotransporter: molecular biology, functional properties, and regulation by WNKs
|
|---|---|
| Published in |
American Journal of Physiology: Renal, Fluid & Electrolyte Physiology, May 2009
|
| DOI | 10.1152/ajprenal.00159.2009 |
| Pubmed ID | |
| Authors |
Gerardo Gamba |
| Abstract |
The thiazide-sensitive Na+-Cl(-) cotransporter is the major salt reabsorption pathway in the distal convoluted tubule, which is located just after the macula densa at the beginning of the aldosterone-sensitive nephron. This cotransporter was identified at the molecular level in the early 1990s by the pioneering work of Steven C. Hebert and coworkers, opening the molecular area, not only for the Na+-Cl(-) cotransporter but also for the family of electroneutral cation-coupled chloride cotransporters that includes the loop diuretic-sensitive Na+-K+-2Cl(-) cotransporter of the thick ascending limb of Henle's loop. This work honoring the memory of Steve Hebert presents a brief review of our current knowledge about salt and water homeostasis generated as a consequence of cloning the cotransporter, with particular emphasis on the molecular biology, physiological properties, human disease due to decreased or increased activity of the cotransporter, and regulation of the cotransporter by a family of serine/threonine kinases known as WNK. Thus one of the legacies of Steve Hebert is a better understanding of salt and water homeostasis. |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | <1% |
| United States | 1 | <1% |
| Philippines | 1 | <1% |
| France | 1 | <1% |
| Unknown | 113 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 15% |
| Student > Bachelor | 17 | 15% |
| Researcher | 15 | 13% |
| Student > Master | 13 | 11% |
| Student > Doctoral Student | 9 | 8% |
| Other | 18 | 15% |
| Unknown | 28 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 26 | 22% |
| Medicine and Dentistry | 24 | 21% |
| Biochemistry, Genetics and Molecular Biology | 14 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Neuroscience | 4 | 3% |
| Other | 17 | 15% |
| Unknown | 26 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2019.
All research outputs
#8,738,637
of 25,870,940 outputs
Outputs from American Journal of Physiology: Renal, Fluid & Electrolyte Physiology
#885
of 2,819 outputs
Outputs of similar age
#42,993
of 124,294 outputs
Outputs of similar age from American Journal of Physiology: Renal, Fluid & Electrolyte Physiology
#9
of 27 outputs
Altmetric has tracked 25,870,940 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,819 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 124,294 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.