Title |
Role of androgens, progestins and tibolone in the treatment of menopausal symptoms: a review of the clinical evidence
|
---|---|
Published in |
Clinical Interventions in Aging, March 2008
|
DOI | 10.2147/cia.s1043 |
Pubmed ID | |
Authors |
Maria Garefalakis, Martha Hickey |
Abstract |
Estrogen-containing hormone therapy (HT) is the most widely prescribed and well-established treatment for menopausal symptoms. High quality evidence confirms that estrogen effectively treats hot flushes, night sweats and vaginal dryness. Progestins are combined with estrogen to prevent endometrial hyperplasia and are sometimes used alone for hot flushes, but are less effective than estrogen for this purpose. Data are conflicting regarding the role of androgens for improving libido and well-being. The synthetic steroid tibolone is widely used in Europe and Australasia and effectively treats hot flushes and vaginal dryness. Tibolone may improve libido more effectively than estrogen containing HT in some women. We summarize the data from studies addressing the efficacy, benefits, and risks of androgens, progestins and tibolone in the treatment of menopausal symptoms. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 2 | 4% |
Israel | 1 | 2% |
Unknown | 53 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 20% |
Student > Ph. D. Student | 8 | 14% |
Student > Postgraduate | 7 | 13% |
Researcher | 5 | 9% |
Professor > Associate Professor | 4 | 7% |
Other | 9 | 16% |
Unknown | 12 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 45% |
Agricultural and Biological Sciences | 4 | 7% |
Chemistry | 4 | 7% |
Psychology | 4 | 7% |
Nursing and Health Professions | 2 | 4% |
Other | 4 | 7% |
Unknown | 13 | 23% |