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Interferon alpha-2a treatment for refractory Behcet uveitis in Korean patients

Overview of attention for article published in BMC Ophthalmology, February 2018
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2 tweeters

Citations

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4 Dimensions

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6 Mendeley
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Title
Interferon alpha-2a treatment for refractory Behcet uveitis in Korean patients
Published in
BMC Ophthalmology, February 2018
DOI 10.1186/s12886-018-0719-0
Pubmed ID
Authors

Ji Hwan Lee, Christopher Seungkyu Lee, Sung Chul Lee

Abstract

To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. This retrospective case series reviewed the medical records of 5 patients with refractory Behcet uveitis from January 2011 to February 2017. IFNα2a was administered at a dose of 3 million IU 3 times per week. Clinical response, relapse rate, and change of visual acuity were evaluated. The mean age of patients was 39.60 ± 9.21 years, and the median treatment duration was 6 months. Four of the 5 patients (80%) presented with responses to IFNα2a without any uveitis attack during the treatment period. The mean number of uveitis attacks/year per patient during the treatment was 0.40 ± 0.89. The mean log of the Minimum Angle of Resolution visual acuity improved from 1.44 ± 0.38 at baseline to 1.02 ± 0.58 at the final follow up. IFNα2a is an effective therapy for Behcet uveitis refractory to conventional immunosuppressants in Korean patients.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 3 50%
Student > Master 2 33%
Professor > Associate Professor 1 17%
Readers by discipline Count As %
Unspecified 3 50%
Medicine and Dentistry 2 33%
Agricultural and Biological Sciences 1 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2018.
All research outputs
#7,529,489
of 12,612,351 outputs
Outputs from BMC Ophthalmology
#250
of 695 outputs
Outputs of similar age
#147,276
of 272,119 outputs
Outputs of similar age from BMC Ophthalmology
#1
of 1 outputs
Altmetric has tracked 12,612,351 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 695 research outputs from this source. They receive a mean Attention Score of 2.3. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 272,119 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them