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Mendeley readers
Attention Score in Context
| Title |
ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal
|
|---|---|
| Published in |
Cancer Cell International, October 2005
|
| DOI | 10.1186/1475-2867-5-30 |
| Pubmed ID | |
| Authors |
Cheol-Hee Choi |
| Abstract |
One of the major problems related with anticancer chemotherapy is resistance against anticancer drugs. The ATP-binding cassette (ABC) transporters are a family of transporter proteins that are responsible for drug resistance and a low bioavailability of drugs by pumping a variety of drugs out cells at the expense of ATP hydrolysis. One strategy for reversal of the resistance of tumor cells expressing ABC transporters is combined use of anticancer drugs with chemosensitizers. In this review, the physiological functions and structures of ABC transporters, and the development of chemosensitizers are described focusing on well-known proteins including P-glycoprotein, multidrug resistance associated protein, and breast cancer resistance protein. |
Mendeley readers
The data shown below were compiled from readership statistics for 423 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Switzerland | 1 | <1% |
| South Africa | 1 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| Mexico | 1 | <1% |
| Argentina | 1 | <1% |
| Belgium | 1 | <1% |
| Unknown | 415 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 89 | 21% |
| Student > Bachelor | 70 | 17% |
| Student > Master | 58 | 14% |
| Researcher | 33 | 8% |
| Student > Doctoral Student | 26 | 6% |
| Other | 45 | 11% |
| Unknown | 102 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 118 | 28% |
| Agricultural and Biological Sciences | 79 | 19% |
| Medicine and Dentistry | 35 | 8% |
| Chemistry | 27 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 23 | 5% |
| Other | 28 | 7% |
| Unknown | 113 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2023.
All research outputs
#2,485,193
of 25,371,288 outputs
Outputs from Cancer Cell International
#57
of 2,231 outputs
Outputs of similar age
#4,416
of 71,166 outputs
Outputs of similar age from Cancer Cell International
#1
of 3 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,231 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 71,166 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them