↓ Skip to main content

Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells

Overview of attention for article published in PLOS ONE, June 2008
Altmetric Badge

Mentioned by

wikipedia
3 Wikipedia pages

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
22 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells
Published in
PLOS ONE, June 2008
DOI 10.1371/journal.pone.0002528
Pubmed ID
Authors

Sabrina Rotolo, Simona Ceccarelli, Ferdinando Romano, Luigi Frati, Cinzia Marchese, Antonio Angeloni

Abstract

Keratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGFR signaling have been linked to the pathogenesis of different epithelial tumors. It has been also hypothesized that its specific ligand, KGF, might contribute to the development of resistance to 5-fluorouracil (5-FU) in epithelial cancers and tamoxifen in estrogen-positive breast cancers.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 18%
Researcher 4 18%
Student > Master 3 14%
Unspecified 2 9%
Student > Ph. D. Student 2 9%
Other 5 23%
Unknown 2 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 32%
Medicine and Dentistry 5 23%
Unspecified 2 9%
Psychology 2 9%
Biochemistry, Genetics and Molecular Biology 2 9%
Other 2 9%
Unknown 2 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2020.
All research outputs
#7,453,827
of 22,787,797 outputs
Outputs from PLOS ONE
#88,757
of 194,524 outputs
Outputs of similar age
#28,614
of 82,275 outputs
Outputs of similar age from PLOS ONE
#293
of 460 outputs
Altmetric has tracked 22,787,797 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 194,524 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 82,275 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 460 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.