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Familial Hemiplegic Migraine CaV2.1 Channel Mutation R192Q Enhances ATP-gated P2X3 Receptor Activity of Mouse Sensory Ganglion Neurons Mediating Trigeminal Pain

Overview of attention for article published in Molecular Pain, January 2010
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2 Wikipedia pages

Citations

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58 Dimensions

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54 Mendeley
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Title
Familial Hemiplegic Migraine CaV2.1 Channel Mutation R192Q Enhances ATP-gated P2X3 Receptor Activity of Mouse Sensory Ganglion Neurons Mediating Trigeminal Pain
Published in
Molecular Pain, January 2010
DOI 10.1186/1744-8069-6-48
Pubmed ID
Authors

Asha Nair, Manuela Simonetti, Nicol Birsa, Michel D Ferrari, Arn MJM van den Maagdenberg, Rashid Giniatullin, Andrea Nistri, Elsa Fabbretti

Abstract

The R192Q mutation of the CACNA1A gene, encoding for the α1 subunit of voltage-gated P/Q Ca2+ channels (Ca(v)2.1), is associated with familial hemiplegic migraine-1. We investigated whether this gain-of-function mutation changed the structure and function of trigeminal neuron P2X3 receptors that are thought to be important contributors to migraine pain.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 2 4%
United Kingdom 1 2%
Unknown 51 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 22%
Student > Ph. D. Student 10 19%
Professor 7 13%
Student > Master 7 13%
Student > Bachelor 5 9%
Other 10 19%
Unknown 3 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 28%
Neuroscience 13 24%
Medicine and Dentistry 12 22%
Biochemistry, Genetics and Molecular Biology 6 11%
Psychology 2 4%
Other 1 2%
Unknown 5 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2023.
All research outputs
#8,535,472
of 25,374,917 outputs
Outputs from Molecular Pain
#190
of 669 outputs
Outputs of similar age
#51,122
of 172,634 outputs
Outputs of similar age from Molecular Pain
#13
of 30 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,634 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.