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Delays, interruptions, and losses from prevention of mother-to-child transmission of HIV services during antenatal care in Johannesburg, South Africa: a cohort analysis

Overview of attention for article published in BMC Infectious Diseases, February 2015
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Title
Delays, interruptions, and losses from prevention of mother-to-child transmission of HIV services during antenatal care in Johannesburg, South Africa: a cohort analysis
Published in
BMC Infectious Diseases, February 2015
DOI 10.1186/s12879-015-0778-2
Pubmed ID
Authors

Kathryn Schnippel, Constance Mongwenyana, Lawrence C Long, Bruce A Larson

Abstract

BackgroundBetween 2010¿2013, South Africa implemented WHO `Option A¿ for prevention of mother to child transmission (PMTCT), where all HIV-infected pregnant women (from 14 weeks gestation) received zidovudine (AZT) as ARV prophylaxis and initiated CD4 testing at their first antenatal care (ANC) visit. After returning for a second visit to collect CD4 results, women with CD4 counts¿¿¿350 were referred to the ART clinic and fast-tracked for initiation on lifelong ART while continuing to visit the ANC clinic every four weeks. Women with CD4 counts >350 were dispensed daily AZT prophylaxis at monthly follow up visits (every 4 weeks). The primary objective of this study was to evaluate adherence of HIV-infected pregnant women to recommended PMTCT services at and after their first antenatal care (ANC) visit.MethodsWe conducted an observational cohort study from August 2012 to February 2013 at two primary health care clinics in Johannesburg, South Africa using routinely collected clinic data from first ANC visit for up to 60 days.ResultsOf the 158 patients newly diagnosed with HIV at their first ANC visit, records indicated that 139 women initiated CD4 testing during their first ANC visit. 52 patients (33% of 158) did not return again to the clinic within 60 days. Of the 118 (84% of 139) women with known gestational age¿>¿13 weeks and known Hb¿¿¿8 g/dl who should have received a 4-week supply of daily AZT at first ANC visit, 81 women (69% of 118) had a record of AZT being dispensed. Among the 139 women with CD4 results, 72 (52%) were eligible for lifelong ART (CD4 count ¿350); however, only 2 initiated ART within 30 days.ConclusionsLoss to initiation of both single and triple ARV therapy, loss to follow-up, and treatment interruptions were common during ANC care for pregnant women with HIV after their first ANC visit.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 2 1%
Unknown 135 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 33 24%
Researcher 23 17%
Student > Ph. D. Student 12 9%
Student > Bachelor 8 6%
Other 8 6%
Other 24 18%
Unknown 29 21%
Readers by discipline Count As %
Medicine and Dentistry 44 32%
Nursing and Health Professions 21 15%
Social Sciences 9 7%
Psychology 7 5%
Agricultural and Biological Sciences 6 4%
Other 18 13%
Unknown 32 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2015.
All research outputs
#17,745,035
of 22,787,797 outputs
Outputs from BMC Infectious Diseases
#5,097
of 7,671 outputs
Outputs of similar age
#242,100
of 352,111 outputs
Outputs of similar age from BMC Infectious Diseases
#91
of 151 outputs
Altmetric has tracked 22,787,797 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,671 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
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We're also able to compare this research output to 151 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.